Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

Fast genetic mapping of complex traits in C. elegans using millions of individuals in bulk

QTL mapping in multicellular animals usually requires generation, maintenance, and phenotyping large panels of recombinant individuals. Here, the authors develop ceX-QTL mapping, a method for fast genetic mapping via bulk selection on millions of unique recombinant C. elegans individuals.

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Detalles Bibliográficos
Autores principales: Alejandro Burga, Eyal Ben-David, Tzitziki Lemus Vergara, James Boocock, Leonid Kruglyak
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/b17ed630d0ca4c1388dd18e8c45b47a7
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