Prediction of population with Alzheimer's disease in the European Union using a system dynamics model
Hana Tomaskova,1 Jitka Kuhnova,2 Richard Cimler,1,3 Ondrej Dolezal,1 Kamil Kuca3 1Faculty of Informatics and Management, 2Faculty of Science, 3Center for Basic and Applied Research (CZAV), University of Hradec Králové, Hradec Králové, Czech Republic Introd...
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Dove Medical Press
2016
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oai:doaj.org-article:b1855791d6414ef68206c7e03b9798cb2021-12-02T08:50:33ZPrediction of population with Alzheimer's disease in the European Union using a system dynamics model1178-2021https://doaj.org/article/b1855791d6414ef68206c7e03b9798cb2016-06-01T00:00:00Zhttps://www.dovepress.com/prediction-of-population-with-alzheimeratildecentiumliquestfrac12iumli-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Hana Tomaskova,1 Jitka Kuhnova,2 Richard Cimler,1,3 Ondrej Dolezal,1 Kamil Kuca3 1Faculty of Informatics and Management, 2Faculty of Science, 3Center for Basic and Applied Research (CZAV), University of Hradec Králové, Hradec Králové, Czech Republic Introduction: Alzheimer’s disease (AD) is a slowly progressing neurodegenerative brain disease with irreversible brain effects; it is the most common cause of dementia. With increasing age, the probability of suffering from AD increases. In this research, population growth of the European Union (EU) until the year 2080 and the number of patients with AD are modeled.Aim: The aim of this research is to predict the spread of AD in the EU population until year 2080 using a computer simulation.Methods: For the simulation of the EU population and the occurrence of AD in this population, a system dynamics modeling approach has been used. System dynamics is a useful and effective method for the investigation of complex social systems. Over the past decades, its applicability has been demonstrated in a wide variety of applications. In this research, this method has been used to investigate the growth of the EU population and predict the number of patients with AD. The model has been calibrated on the population prediction data created by Eurostat.Results: Based on data from Eurostat, the EU population until year 2080 has been modeled. In 2013, the population of the EU was 508 million and the number of patients with AD was 7.5 million. Based on the prediction, in 2040, the population of the EU will be 524 million and the number of patients with AD will be 13.1 million. By the year 2080, the EU population will be 520 million and the number of patients with AD will be 13.7 million.Conclusion: System dynamics modeling approach has been used for the prediction of the number of patients with AD in the EU population till the year 2080. These results can be used to determine the economic burden of the treatment of these patients. With different input data, the simulation can be used also for the different regions as well as for different noncontagious disease predictions. Keywords: Alzheimer’s disease, population modeling, system dynamics, prediction modelTomaskova HKuhnova JCimler RDolezal OKuca KDove Medical PressarticleAlzheimer diseasepopulation modelingsystem dynam- icsprediction modelNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2016, Iss Issue 1, Pp 1589-1598 (2016) |
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| collection |
DOAJ |
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EN |
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Alzheimer disease population modeling system dynam- ics prediction model Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
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Alzheimer disease population modeling system dynam- ics prediction model Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Tomaskova H Kuhnova J Cimler R Dolezal O Kuca K Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| description |
Hana Tomaskova,1 Jitka Kuhnova,2 Richard Cimler,1,3 Ondrej Dolezal,1 Kamil Kuca3 1Faculty of Informatics and Management, 2Faculty of Science, 3Center for Basic and Applied Research (CZAV), University of Hradec Králové, Hradec Králové, Czech Republic Introduction: Alzheimer’s disease (AD) is a slowly progressing neurodegenerative brain disease with irreversible brain effects; it is the most common cause of dementia. With increasing age, the probability of suffering from AD increases. In this research, population growth of the European Union (EU) until the year 2080 and the number of patients with AD are modeled.Aim: The aim of this research is to predict the spread of AD in the EU population until year 2080 using a computer simulation.Methods: For the simulation of the EU population and the occurrence of AD in this population, a system dynamics modeling approach has been used. System dynamics is a useful and effective method for the investigation of complex social systems. Over the past decades, its applicability has been demonstrated in a wide variety of applications. In this research, this method has been used to investigate the growth of the EU population and predict the number of patients with AD. The model has been calibrated on the population prediction data created by Eurostat.Results: Based on data from Eurostat, the EU population until year 2080 has been modeled. In 2013, the population of the EU was 508 million and the number of patients with AD was 7.5 million. Based on the prediction, in 2040, the population of the EU will be 524 million and the number of patients with AD will be 13.1 million. By the year 2080, the EU population will be 520 million and the number of patients with AD will be 13.7 million.Conclusion: System dynamics modeling approach has been used for the prediction of the number of patients with AD in the EU population till the year 2080. These results can be used to determine the economic burden of the treatment of these patients. With different input data, the simulation can be used also for the different regions as well as for different noncontagious disease predictions. Keywords: Alzheimer’s disease, population modeling, system dynamics, prediction model |
| format |
article |
| author |
Tomaskova H Kuhnova J Cimler R Dolezal O Kuca K |
| author_facet |
Tomaskova H Kuhnova J Cimler R Dolezal O Kuca K |
| author_sort |
Tomaskova H |
| title |
Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| title_short |
Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| title_full |
Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| title_fullStr |
Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| title_full_unstemmed |
Prediction of population with Alzheimer's disease in the European Union using a system dynamics model |
| title_sort |
prediction of population with alzheimer's disease in the european union using a system dynamics model |
| publisher |
Dove Medical Press |
| publishDate |
2016 |
| url |
https://doaj.org/article/b1855791d6414ef68206c7e03b9798cb |
| work_keys_str_mv |
AT tomaskovah predictionofpopulationwithalzheimer39sdiseaseintheeuropeanunionusingasystemdynamicsmodel AT kuhnovaj predictionofpopulationwithalzheimer39sdiseaseintheeuropeanunionusingasystemdynamicsmodel AT cimlerr predictionofpopulationwithalzheimer39sdiseaseintheeuropeanunionusingasystemdynamicsmodel AT dolezalo predictionofpopulationwithalzheimer39sdiseaseintheeuropeanunionusingasystemdynamicsmodel AT kucak predictionofpopulationwithalzheimer39sdiseaseintheeuropeanunionusingasystemdynamicsmodel |
| _version_ |
1718398384582164480 |