Malaria Induces Anemia through CD8<sup>+</sup> T Cell-Dependent Parasite Clearance and Erythrocyte Removal in the Spleen

ABSTRACT  Severe malarial anemia (SMA) in semi-immune individuals eliminates both infected and uninfected erythrocytes and is a frequent fatal complication. It is proportional not to circulating parasitemia but total parasite mass (sequestered) in the organs. Thus, immune responses that clear parasi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Innocent Safeukui, Noé D. Gomez, Aanuoluwa A. Adelani, Florence Burte, Nathaniel K. Afolabi, Rama Akondy, Peter Velazquez, Anthony Holder, Rita Tewari, Pierre Buffet, Biobele J. Brown, Wuraola A. Shokunbi, David Olaleye, Olugbemiro Sodeinde, James Kazura, Rafi Ahmed, Narla Mohandas, Delmiro Fernandez-Reyes, Kasturi Haldar
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://doaj.org/article/b18bccfedc1f46e3a03ecd402fa15bf1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!