Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients

Adenoid cystic carcinoma (AdCC) is a common tumour of the minor salivary gland, rarely seen in other anatomical locations. In particular, AdCC of the breast accounts for < 0.1% of patients diagnosed with breast cancer. Here we report our institutional experience with three cases of breast AdCC di...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Julia M. Sołek, Marcin Braun, Marta Kalwas, Dorota Jesionek-Kupnicka, Hanna Romańska
Formato:	article
Lenguaje:	EN
Publicado:	Termedia Publishing House 2020
Materias:	adenoid cystic carcinoma breast cancer histopathology. Medicine R
Acceso en línea:	https://doaj.org/article/b19172ea5a2349e88d3e783a5b78e7b6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b19172ea5a2349e88d3e783a5b78e7b6
record_format	dspace
spelling	oai:doaj.org-article:b19172ea5a2349e88d3e783a5b78e7b62021-12-02T19:19:18ZAdenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients1428-25261897-430910.5114/wo.2020.99025https://doaj.org/article/b19172ea5a2349e88d3e783a5b78e7b62020-09-01T00:00:00Zhttps://www.termedia.pl/Adenoid-cystic-carcinoma-of-the-breast-an-uncommon-malignancy-r-nwith-unpredictable-clinical-behaviour-A-case-series-of-three-patients,3,41789,1,1.htmlhttps://doaj.org/toc/1428-2526https://doaj.org/toc/1897-4309Adenoid cystic carcinoma (AdCC) is a common tumour of the minor salivary gland, rarely seen in other anatomical locations. In particular, AdCC of the breast accounts for < 0.1% of patients diagnosed with breast cancer. Here we report our institutional experience with three cases of breast AdCC diagnosed between 2009 and 2017. Mean age of women included in the report was 53 (range from 41 to 62). One case was of no special subtype, two were solid variants and one presented with a component of invasive ductal carcinoma. At diagnosis in all cases neither lymph node involvement nor distal metastases were detected. All patients underwent surgical resection of the tumour – mastectomy or lumpectomy, followed by either adjuvant radiotherapy and chemotherapy (one case), chemotherapy without radiotherapy (one case) or no treatment (one case). Two patients were reported to develop metastatic disease. No deaths were recorded. In contrast to other anatomical locations AdCC of the breast is regarded as a rare tumour with low malignant potential. However, as shown in our case series, it can present as an aggressive disease with distal metastases, which calls for deep awareness among both pathologists and clinicians involved in the process of diagnosis and therapy.Julia M. SołekMarcin BraunMarta KalwasDorota Jesionek-KupnickaHanna RomańskaTermedia Publishing Housearticleadenoid cystic carcinoma breast cancer histopathology.MedicineRENContemporary Oncology, Vol 24, Iss 4, Pp 263-265 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	adenoid cystic carcinoma breast cancer histopathology. Medicine R
spellingShingle	adenoid cystic carcinoma breast cancer histopathology. Medicine R Julia M. Sołek Marcin Braun Marta Kalwas Dorota Jesionek-Kupnicka Hanna Romańska Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
description	Adenoid cystic carcinoma (AdCC) is a common tumour of the minor salivary gland, rarely seen in other anatomical locations. In particular, AdCC of the breast accounts for < 0.1% of patients diagnosed with breast cancer. Here we report our institutional experience with three cases of breast AdCC diagnosed between 2009 and 2017. Mean age of women included in the report was 53 (range from 41 to 62). One case was of no special subtype, two were solid variants and one presented with a component of invasive ductal carcinoma. At diagnosis in all cases neither lymph node involvement nor distal metastases were detected. All patients underwent surgical resection of the tumour – mastectomy or lumpectomy, followed by either adjuvant radiotherapy and chemotherapy (one case), chemotherapy without radiotherapy (one case) or no treatment (one case). Two patients were reported to develop metastatic disease. No deaths were recorded. In contrast to other anatomical locations AdCC of the breast is regarded as a rare tumour with low malignant potential. However, as shown in our case series, it can present as an aggressive disease with distal metastases, which calls for deep awareness among both pathologists and clinicians involved in the process of diagnosis and therapy.
format	article
author	Julia M. Sołek Marcin Braun Marta Kalwas Dorota Jesionek-Kupnicka Hanna Romańska
author_facet	Julia M. Sołek Marcin Braun Marta Kalwas Dorota Jesionek-Kupnicka Hanna Romańska
author_sort	Julia M. Sołek
title	Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
title_short	Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
title_full	Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
title_fullStr	Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
title_full_unstemmed	Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients
title_sort	adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. a case series of three patients
publisher	Termedia Publishing House
publishDate	2020
url	https://doaj.org/article/b19172ea5a2349e88d3e783a5b78e7b6
work_keys_str_mv	AT juliamsołek adenoidcysticcarcinomaofthebreastanuncommonmalignancywithunpredictableclinicalbehaviouracaseseriesofthreepatients AT marcinbraun adenoidcysticcarcinomaofthebreastanuncommonmalignancywithunpredictableclinicalbehaviouracaseseriesofthreepatients AT martakalwas adenoidcysticcarcinomaofthebreastanuncommonmalignancywithunpredictableclinicalbehaviouracaseseriesofthreepatients AT dorotajesionekkupnicka adenoidcysticcarcinomaofthebreastanuncommonmalignancywithunpredictableclinicalbehaviouracaseseriesofthreepatients AT hannaromanska adenoidcysticcarcinomaofthebreastanuncommonmalignancywithunpredictableclinicalbehaviouracaseseriesofthreepatients
_version_	1718376872929132544

Adenoid cystic carcinoma of the breast – an uncommon malignancy with unpredictable clinical behaviour. A case series of three patients

Ejemplares similares