Renoprotective Effect of Formononetin by Suppressing Smad3 Expression in Db/Db Mice

QR Code

Renoprotective Effect of Formononetin by Suppressing Smad3 Expression in Db/Db Mice

Jiawei Lv,1 Kai Zhuang,1 Xiyu Jiang,1 Heqing Huang,1,2 Shijian Quan1 1Department of Pharmacology, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, People’s Republic of China; 2Laboratory of Pharmacology & Toxicology, School of Pharmaceu...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Lv J, Zhuang K, Jiang X, Huang H, Quan S
Format:	article
Langue:	EN
Publié:	Dove Medical Press 2020
Sujets:	formononetin diabetic nephropathy db/db mice renal fibrosis expression of smad3 antioxidants Specialties of internal medicine RC581-951
Accès en ligne:	https://doaj.org/article/b1a10d2d3e5b4d22a80a21ddc8819032
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Alpinia oxyphylla Miq. extract changes miRNA expression profiles in db-/db- mouse kidney
par: Du,Guankui, et autres
Publié: (2017)

A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
par: Zhang C, et autres
Publié: (2019)

Valsartan alleviates the blood–brain barrier dysfunction in db/db diabetic mice
par: Longxue Cai, et autres
Publié: (2021)

Demethylbellidifolin, a potential aldose reductase inhibitor ameliorates diabetic nephropathy by regulating the polyol pathway
par: Haifei Xie, et autres
Publié: (2022)

Anti-inflammatory and angiogenic effects of exercise training in cardiac muscle of diabetic mice
par: Broderick TL, et autres
Publié: (2019)

On the Modeling of Microstrip Lines Loaded With Dumbbell Defect-Ground-Structure (DB-DGS) and Folded DB-DGS Resonators
par: Lijuan Su, et autres
Publié: (2021)

The effects of exercise training and caloric restriction on the cardiac oxytocin natriuretic peptide system in the diabetic mouse
par: Broderick TL, et autres
Publié: (2017)

Astragalus–Saffron–Rhubarb Mixture Delays the Progress of Diabetic Nephropathy in db/db Mice
par: Zhou XC, et autres
Publié: (2021)

Design of a Wideband dB-Linear Variable Gain Amplifier With Continuous Gain Adjusting in 90-nm CMOS Technology
par: Chenxuan Fan, et autres
Publié: (2021)

Artemether Regulates Metaflammation to Improve Glycolipid Metabolism in db/db Mice
par: Fu W, et autres
Publié: (2020)

Qihu Preparation Ameliorates Diabetes by Activating the AMPK Signaling Pathway in db/db Mice
par: Zeng H, et autres
Publié: (2021)

High-Intensity Interval Training Attenuates Ketogenic Diet-Induced Liver Fibrosis in Type 2 Diabetic Mice by Ameliorating TGF-β1/Smad Signaling
par: Zhang Q, et autres
Publié: (2020)

Comprehensive Characterization of the Coding and Non-Coding Single Nucleotide Polymorphisms in the Tumor Protein p63 (TP63) Gene Using In Silico Tools
par: Shamima Akter, et autres
Publié: (2021)

Isoliquiritigenin attenuates acute renal injury through suppressing oxidative stress, fibrosis and JAK2/STAT3 pathway in streptozotocin-induced diabetic rats
par: Leiming Sun, et autres
Publié: (2021)

Electromagnetic Fields Ameliorate Insulin Resistance and Hepatic Steatosis by Modulating Redox Homeostasis and SREBP-1c Expression in db/db Mice
par: Zhai M, et autres
Publié: (2021)

Ursolic Acid Treatment Alleviates Diabetic Kidney Injury By Regulating The ARAP1/AT1R Signaling Pathway
par: Ma TK, et autres
Publié: (2019)

Branched Chain Amino Acids Protects Rat Mesangial Cells from High Glucose by Modulating TGF-β1 and BMP-7
par: Zhang X, et autres
Publié: (2019)

Branched Chain Amino Acids Protects Rat Mesangial Cells from High Glucose by Modulating TGF-β1 and BMP-7 [Corrigendum]
par: Zhang X, et autres
Publié: (2020)

Dihydromyricetin Attenuates Metabolic Syndrome And Improves Insulin Sensitivity By Upregulating Insulin Receptor Substrate-1 (Y612) Tyrosine Phosphorylation In db/db Mice
par: He J, et autres
Publié: (2019)

Low-Magnitude High-Frequency Vibration Decreases Body Weight Gain and Increases Muscle Strength by Enhancing the p38 and AMPK Pathways in db/db Mice
par: Ren Z, et autres
Publié: (2020)

Genotyping and Molecular Characterization of Infectious Bursal Disease Virus Identified in Important Poultry-Raising Areas of China During 2019 and 2020
par: Nan Jiang, et autres
Publié: (2021)

Influence of type-4 dipeptidyl peptidase inhibition on endothelium-dependent relaxation of aortae from a db/db mouse model of type 2 diabetes: a comparison with the effect of glimepiride
par: Woodman OL, et autres
Publié: (2019)

Blood Glucose and Renal Function Evaluation in Patients with Viral Hepatitis
par: Hsu WT, et autres
Publié: (2021)

Inhibition of Sirt2 Alleviates Fibroblasts Activation and Pulmonary Fibrosis via Smad2/3 Pathway
par: Hui Gong, et autres
Publié: (2021)

A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats
par: Tojo A, et autres
Publié: (2016)

Silica nanoparticles induce liver fibrosis via TGF-β1/Smad3 pathway in ICR mice
par: Yu Y, et autres
Publié: (2017)

LncRNA NNT-AS1 regulates proliferation, ECM accumulation and inflammation of human mesangial cells induced by high glucose through miR-214-5p/smad4
par: Zhuang Geng, et autres
Publié: (2021)

CircSMAD4 alleviates high glucose-induced inflammation, extracellular matrix deposition and apoptosis in mouse glomerulus mesangial cells by relieving miR-377-3p-mediated BMP7 inhibition
par: Rina Wu, et autres
Publié: (2021)

Downregulation of TGF-β1 suppressed proliferation and increased chemosensitivity of ovarian cancer cells by promoting BRCA1/Smad3 signaling
par: Wang,Yanqiu, et autres
Publié: (2018)

Quercetin improves lipid metabolism via SCAP-SREBP2-LDLr signaling pathway in early stage diabetic nephropathy
par: Jiang X, et autres
Publié: (2019)

Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3
par: Yiyu Qin, et autres
Publié: (2021)

The Renoprotective Effects of Naringenin (NGN) in Gestational Pregnancy
par: Zhao C, et autres
Publié: (2020)

Sinomenine Relieves Airway Remodeling By Inhibiting Epithelial-Mesenchymal Transition Through Downregulating TGF-β1 and Smad3 Expression In Vitro and In Vivo
par: Hongjuan He, et autres
Publié: (2021)

Bile cast nephropathy
par: Shakiba Hassanzadeh, et autres
Publié: (2022)

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
par: Xue M, et autres
Publié: (2015)

The antidiabetic effects of a dry powder of dietary vegetable and fruit mixtures in diabetic db/db mice
par: Chung-Man Yeung, et autres
Publié: (2008)

Curcumin restores mitochondrial functions and decreases lipid peroxidation in liver and kidneys of diabetic db/db mice
par: Soto-Urquieta,María G, et autres
Publié: (2014)

GPR37 promotes the malignancy of lung adenocarcinoma via TGF-β/Smad pathway
par: Wang Jian, et autres
Publié: (2020)

Corrigendum: ErHuang Formula Improves Renal Fibrosis in Diabetic Nephropathy Rats by Inhibiting CXCL6/JAK/STAT3 Signaling Pathway
par: Yu-Li Shen, et autres
Publié: (2021)

Silencing of KCNQ1OT1 Decreases Oxidative Stress and Pyroptosis of Renal Tubular Epithelial Cells
par: Zhu B, et autres
Publié: (2020)