A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection

A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection

Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4.

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Autores principales: Chunlai Cui, Yan Wang, Jingnan Liu, Jing Zhao, Peilu Sun, Sibao Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d
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spelling oai:doaj.org-article:b1a618ff0f2441b9a5117839d2cd232d2021-12-02T17:01:33ZA fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection10.1038/s41467-019-12323-12041-1723https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12323-1https://doaj.org/toc/2041-1723Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4.Chunlai CuiYan WangJingnan LiuJing ZhaoPeilu SunSibao WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Chunlai Cui
Yan Wang
Jingnan Liu
Jing Zhao
Peilu Sun
Sibao Wang
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
description Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4.
format article
author Chunlai Cui
Yan Wang
Jingnan Liu
Jing Zhao
Peilu Sun
Sibao Wang
author_facet Chunlai Cui
Yan Wang
Jingnan Liu
Jing Zhao
Peilu Sun
Sibao Wang
author_sort Chunlai Cui
title A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
title_short A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
title_full A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
title_fullStr A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
title_full_unstemmed A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
title_sort fungal pathogen deploys a small silencing rna that attenuates mosquito immunity and facilitates infection
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d
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AT jingzhao afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection
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