A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection
Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4.
Enregistré dans:
Auteurs principaux: | , , , , , |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
id |
oai:doaj.org-article:b1a618ff0f2441b9a5117839d2cd232d |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b1a618ff0f2441b9a5117839d2cd232d2021-12-02T17:01:33ZA fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection10.1038/s41467-019-12323-12041-1723https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12323-1https://doaj.org/toc/2041-1723Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4.Chunlai CuiYan WangJingnan LiuJing ZhaoPeilu SunSibao WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Chunlai Cui Yan Wang Jingnan Liu Jing Zhao Peilu Sun Sibao Wang A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
description |
Fungi that infect insects can potentially be exploited for disease vector control. Here the authors show that the fungus Beauveria bassiana exports a microRNA-like RNA into mosquito cells that modulates host immunity by suppressing expression of Toll receptor ligand Spätzle 4. |
format |
article |
author |
Chunlai Cui Yan Wang Jingnan Liu Jing Zhao Peilu Sun Sibao Wang |
author_facet |
Chunlai Cui Yan Wang Jingnan Liu Jing Zhao Peilu Sun Sibao Wang |
author_sort |
Chunlai Cui |
title |
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
title_short |
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
title_full |
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
title_fullStr |
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
title_full_unstemmed |
A fungal pathogen deploys a small silencing RNA that attenuates mosquito immunity and facilitates infection |
title_sort |
fungal pathogen deploys a small silencing rna that attenuates mosquito immunity and facilitates infection |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/b1a618ff0f2441b9a5117839d2cd232d |
work_keys_str_mv |
AT chunlaicui afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT yanwang afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT jingnanliu afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT jingzhao afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT peilusun afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT sibaowang afungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT chunlaicui fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT yanwang fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT jingnanliu fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT jingzhao fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT peilusun fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection AT sibaowang fungalpathogendeploysasmallsilencingrnathatattenuatesmosquitoimmunityandfacilitatesinfection |
_version_ |
1718382106823884800 |