Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces

We developed a prodrug type of curcumin, curcumin monoglucuronide (CMG), whose intravenous/intraperitoneal injection achieves a high serum concentration of free-form curcumin. Although curcumin has been reported to alter the gut microbiota and immune responses, it is unclear whether the altered micr...

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Autores principales: Sundar Khadka, Seiichi Omura, Fumitaka Sato, Kazuto Nishio, Hideaki Kakeya, Ikuo Tsunoda
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/b1ab5539dccd4d6489c288f6f55bc212
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