Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region

100 children were observed. Tuberculosis of inrathoracic lymph nodes was found in 79 (79,0 %) patients, complicated tuberculosis - in 29 (36,7 %) of 79 patients. The phase of reverse development of tuberculosis was detected in 47,0 % of children with TB. Due to the slow dynamics of the disease, the...

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Autores principales:	S. G. Zvonkova, E. Y. Zorkaltseva, S. V. Pugacheva
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	tuberculosis in children treatment of tuberculosis Science Q
Acceso en línea:	https://doaj.org/article/b1ad7b2d79354492935df7ee7235827a
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spelling	oai:doaj.org-article:b1ad7b2d79354492935df7ee7235827a2021-11-23T06:14:33ZClinical manifestations and outcomes of tuberculosis in children in the Irkutsk region2541-94202587-959610.12737/20557https://doaj.org/article/b1ad7b2d79354492935df7ee7235827a2016-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/162https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596100 children were observed. Tuberculosis of inrathoracic lymph nodes was found in 79 (79,0 %) patients, complicated tuberculosis - in 29 (36,7 %) of 79 patients. The phase of reverse development of tuberculosis was detected in 47,0 % of children with TB. Due to the slow dynamics of the disease, the duration of chemotherapy in 75,0 % of children was 240 days. In the mode of treatment, drug resistance of a patient in lesion of tuberculosis infection is taken into account. As a result of treatment, resorption of infiltration in the lungs was observed in 15,0 %, fibrosis - in 26,0 %, formation of small calcifications - in 39,0 %, formation of multiple large calcifications - in 20,0 % of children. The cause of the formation of calcifications is the late detection of tuberculosis. In children with the formation of calcifications throughout the course of treatment the number of leukocytes decreased, the downward trend in the absolute number of lymphocytes to the 4th month of treatment was traced, the content of leukocytes increased to the end of primary treatment. In children without formation of calcifications the reduction of leukocytes and lymphocytes was not identified during the treatment. The decrease in the content of leukocytes and lymphocytes may explain long-term persistence of endogenous intoxication.S. G. ZvonkovaE. Y. ZorkaltsevaS. V. PugachevaScientific Сentre for Family Health and Human Reproduction Problemsarticletuberculosis in childrentreatment of tuberculosisScienceQRUActa Biomedica Scientifica, Vol 1, Iss 2, Pp 12-15 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	tuberculosis in children treatment of tuberculosis Science Q
spellingShingle	tuberculosis in children treatment of tuberculosis Science Q S. G. Zvonkova E. Y. Zorkaltseva S. V. Pugacheva Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
description	100 children were observed. Tuberculosis of inrathoracic lymph nodes was found in 79 (79,0 %) patients, complicated tuberculosis - in 29 (36,7 %) of 79 patients. The phase of reverse development of tuberculosis was detected in 47,0 % of children with TB. Due to the slow dynamics of the disease, the duration of chemotherapy in 75,0 % of children was 240 days. In the mode of treatment, drug resistance of a patient in lesion of tuberculosis infection is taken into account. As a result of treatment, resorption of infiltration in the lungs was observed in 15,0 %, fibrosis - in 26,0 %, formation of small calcifications - in 39,0 %, formation of multiple large calcifications - in 20,0 % of children. The cause of the formation of calcifications is the late detection of tuberculosis. In children with the formation of calcifications throughout the course of treatment the number of leukocytes decreased, the downward trend in the absolute number of lymphocytes to the 4th month of treatment was traced, the content of leukocytes increased to the end of primary treatment. In children without formation of calcifications the reduction of leukocytes and lymphocytes was not identified during the treatment. The decrease in the content of leukocytes and lymphocytes may explain long-term persistence of endogenous intoxication.
format	article
author	S. G. Zvonkova E. Y. Zorkaltseva S. V. Pugacheva
author_facet	S. G. Zvonkova E. Y. Zorkaltseva S. V. Pugacheva
author_sort	S. G. Zvonkova
title	Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
title_short	Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
title_full	Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
title_fullStr	Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
title_full_unstemmed	Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region
title_sort	clinical manifestations and outcomes of tuberculosis in children in the irkutsk region
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/b1ad7b2d79354492935df7ee7235827a
work_keys_str_mv	AT sgzvonkova clinicalmanifestationsandoutcomesoftuberculosisinchildrenintheirkutskregion AT eyzorkaltseva clinicalmanifestationsandoutcomesoftuberculosisinchildrenintheirkutskregion AT svpugacheva clinicalmanifestationsandoutcomesoftuberculosisinchildrenintheirkutskregion
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Clinical manifestations and outcomes of tuberculosis in children in the Irkutsk region

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