Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons

The vCA1-BA projection is enriched in shock responsive neurons, which are necessary for fear memory encoding and become correlated with a network of neurons during retrieval. Here the authors show that the magnitude of vCA1 correlated activity is proportional to memory strength and requires the shoc...

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Auteurs principaux: Jessica C. Jimenez, Jack E. Berry, Sean C. Lim, Samantha K. Ong, Mazen A. Kheirbek, Rene Hen
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/b1ae9cbb452a4a1cb40c60fdbc9c5b59
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Résumé:The vCA1-BA projection is enriched in shock responsive neurons, which are necessary for fear memory encoding and become correlated with a network of neurons during retrieval. Here the authors show that the magnitude of vCA1 correlated activity is proportional to memory strength and requires the shock response during encoding.