Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter

Dopamine release in the striatum has important roles in action selection and in disorders such as Parkinson’s disease. The authors here show that short-term plasticity of dopamine release is strongly determined by axonal activation and dopamine transporters.

Guardado en:
Detalles Bibliográficos
Autores principales: Mark D. Condon, Nicola J. Platt, Yan-Feng Zhang, Bradley M. Roberts, Michael A. Clements, Stefania Vietti-Michelina, Min-Yee Tseu, Katherine R. Brimblecombe, Sarah Threlfell, Edward O. Mann, Stephanie J. Cragg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/b1b396a19d0e49f0914ab423562f96e0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:b1b396a19d0e49f0914ab423562f96e0
record_format dspace
spelling oai:doaj.org-article:b1b396a19d0e49f0914ab423562f96e02021-12-02T16:58:04ZPlasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter10.1038/s41467-019-12264-92041-1723https://doaj.org/article/b1b396a19d0e49f0914ab423562f96e02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12264-9https://doaj.org/toc/2041-1723Dopamine release in the striatum has important roles in action selection and in disorders such as Parkinson’s disease. The authors here show that short-term plasticity of dopamine release is strongly determined by axonal activation and dopamine transporters.Mark D. CondonNicola J. PlattYan-Feng ZhangBradley M. RobertsMichael A. ClementsStefania Vietti-MichelinaMin-Yee TseuKatherine R. BrimblecombeSarah ThrelfellEdward O. MannStephanie J. CraggNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Mark D. Condon
Nicola J. Platt
Yan-Feng Zhang
Bradley M. Roberts
Michael A. Clements
Stefania Vietti-Michelina
Min-Yee Tseu
Katherine R. Brimblecombe
Sarah Threlfell
Edward O. Mann
Stephanie J. Cragg
Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
description Dopamine release in the striatum has important roles in action selection and in disorders such as Parkinson’s disease. The authors here show that short-term plasticity of dopamine release is strongly determined by axonal activation and dopamine transporters.
format article
author Mark D. Condon
Nicola J. Platt
Yan-Feng Zhang
Bradley M. Roberts
Michael A. Clements
Stefania Vietti-Michelina
Min-Yee Tseu
Katherine R. Brimblecombe
Sarah Threlfell
Edward O. Mann
Stephanie J. Cragg
author_facet Mark D. Condon
Nicola J. Platt
Yan-Feng Zhang
Bradley M. Roberts
Michael A. Clements
Stefania Vietti-Michelina
Min-Yee Tseu
Katherine R. Brimblecombe
Sarah Threlfell
Edward O. Mann
Stephanie J. Cragg
author_sort Mark D. Condon
title Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
title_short Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
title_full Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
title_fullStr Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
title_full_unstemmed Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
title_sort plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/b1b396a19d0e49f0914ab423562f96e0
work_keys_str_mv AT markdcondon plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT nicolajplatt plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT yanfengzhang plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT bradleymroberts plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT michaelaclements plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT stefaniaviettimichelina plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT minyeetseu plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT katherinerbrimblecombe plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT sarahthrelfell plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT edwardomann plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
AT stephaniejcragg plasticityinstriataldopaminereleaseisgovernedbyreleaseindependentdepressionandthedopaminetransporter
_version_ 1718382409216425984