Discovery of the <named-content content-type="genus-species">Pseudomonas</named-content> Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

QR Code

Discovery of the <named-content content-type="genus-species">Pseudomonas</named-content> Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

ABSTRACT Natural products that possess alkyne or polyyne moieties have been isolated from a variety of biological sources and possess a broad a range of bioactivities. In bacteria, the basic biosynthesis of polyynes is known, but their biosynthetic gene cluster (BGC) distribution and evolutionary re...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Alex J. Mullins, Gordon Webster, Hak Joong Kim, Jinlian Zhao, Yoana D. Petrova, Christina E. Ramming, Matthew Jenner, James A. H. Murray, Thomas R. Connor, Christian Hertweck, Gregory L. Challis, Eshwar Mahenthiralingam
Format:	article
Langue:	EN
Publié:	American Society for Microbiology 2021
Sujets:	Pseudomonas biosynthetic gene clusters natural products phylogenetics polyynes Microbiology QR1-502
Accès en ligne:	https://doaj.org/article/b1b4253ed1464c9da85b6b1a1b4667c8
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Phylogenetic Distribution of Secondary Metabolites in the <named-content content-type="genus-species">Bacillus subtilis</named-content> Species Complex
par: Kat Steinke, et autres
Publié: (2021)

Genomic and Chemical Diversity of <named-content content-type="genus-species">Bacillus subtilis</named-content> Secondary Metabolites against Plant Pathogenic Fungi
par: Heiko T. Kiesewalter, et autres
Publié: (2021)

An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
par: Abigail L. Lind, et autres
Publié: (2018)

Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in <named-content content-type="genus-species">Chlamydia trachomatis</named-content>
par: Hayley E. Young, et autres
Publié: (2016)

Whole-Genome Sequencing of Human Clinical <named-content content-type="genus-species">Klebsiella pneumoniae</named-content> Isolates Reveals Misidentification and Misunderstandings of <named-content content-type="genus-species">Klebsiella pneumoniae</named-content>, <named-content content-type="genus-species">Klebsiella variicola</named-content>, and <named-content content-type="genus-species">Klebsiella quasipneumoniae</named-content>
par: S. Wesley Long, et autres
Publié: (2017)

Whole-Genome Identification and Comparative Expression Analysis of Anthocyanin Biosynthetic Genes in Brassica napus
par: Dan He, et autres
Publié: (2021)

Adaptive Evolution of <named-content content-type="genus-species">Geobacter sulfurreducens</named-content> in Coculture with <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
par: Lucie Semenec, et autres
Publié: (2020)

Interspecies Interactions between <named-content content-type="genus-species">Clostridium difficile</named-content> and <named-content content-type="genus-species">Candida albicans</named-content>
par: Pim T. van Leeuwen, et autres
Publié: (2016)

Identification of Virulence-Associated Properties by Comparative Genome Analysis of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>, <named-content content-type="genus-species">S. pseudopneumoniae</named-content>, <named-content content-type="genus-species">S. mitis</named-content>, Three <named-content content-type="genus-species">S. oralis</named-content> Subspecies, and <italic toggle="yes">S. infantis</italic>
par: Mogens Kilian, et autres
Publié: (2019)

Potential secondary metabolite biosynthetic gene clusters and antibacterial activity of novel taxa Gandjariella
par: Fitria Ningsih, et autres
Publié: (2020)

Parallel Evolution of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> and <named-content content-type="genus-species">Streptococcus mitis</named-content> to Pathogenic and Mutualistic Lifestyles
par: Mogens Kilian, et autres
Publié: (2014)

Monoassociation with <named-content content-type="genus-species">Lactobacillus plantarum</named-content> Disrupts Intestinal Homeostasis in Adult <named-content content-type="genus-species">Drosophila melanogaster</named-content>
par: David Fast, et autres
Publié: (2018)

Control of <named-content content-type="genus-species">Candida albicans</named-content> Metabolism and Biofilm Formation by <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Phenazines
par: Diana K. Morales, et autres
Publié: (2013)

Continental Drift and Speciation of the <named-content content-type="genus-species">Cryptococcus neoformans</named-content> and <named-content content-type="genus-species">Cryptococcus gattii</named-content> Species Complexes
par: Arturo Casadevall, et autres
Publié: (2017)

The Eukaryotic Host Factor 14-3-3 Inactivates Adenylate Cyclase Toxins of <named-content content-type="genus-species">Bordetella bronchiseptica</named-content> and <named-content content-type="genus-species">B. parapertussis</named-content>, but Not <named-content content-type="genus-species">B. pertussis</named-content>
par: Aya Fukui-Miyazaki, et autres
Publié: (2018)

Advances in Phenazines over the Past Decade: Review of Their Pharmacological Activities, Mechanisms of Action, Biosynthetic Pathways and Synthetic Strategies
par: Junjie Yan, et autres
Publié: (2021)

Commensal Protection of <named-content content-type="genus-species">Staphylococcus aureus</named-content> against Antimicrobials by <named-content content-type="genus-species">Candida albicans</named-content> Biofilm Matrix
par: Eric F. Kong, et autres
Publié: (2016)

Gut Microbial and Metabolic Responses to <named-content content-type="genus-species">Salmonella enterica</named-content> Serovar Typhimurium and <named-content content-type="genus-species">Candida albicans</named-content>
par: Jennifer R. Bratburd, et autres
Publié: (2018)

MreB Forms Subdiffraction Nanofilaments during Active Growth in <named-content content-type="genus-species">Bacillus</named-content><named-content content-type="genus-species"> subtilis</named-content>
par: Cyrille Billaudeau, et autres
Publié: (2019)

Oxalate-Degrading <named-content content-type="genus-species">Bacillus subtilis</named-content> Mitigates Urolithiasis in a <named-content content-type="genus-species">Drosophila melanogaster</named-content> Model
par: Kait F. Al, et autres
Publié: (2020)

<named-content content-type="genus-species">Burkholderia ubonensis</named-content> Meropenem Resistance: Insights into Distinct Properties of Class A β-Lactamases in <named-content content-type="genus-species">Burkholderia cepacia</named-content> Complex and <named-content content-type="genus-species">Burkholderia pseudomallei</named-content> Complex Bacteria
par: Nawarat Somprasong, et autres
Publié: (2020)

Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease
par: Gajender Aleti, et autres
Publié: (2019)

<named-content content-type="genus-species">Staphylococcus aureus</named-content> Protein A Mediates Interspecies Interactions at the Cell Surface of <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content>
par: Catherine R. Armbruster, et autres
Publié: (2016)

Volatile Compounds Emitted by <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Stimulate Growth of the Fungal Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content>
par: Benoit Briard, et autres
Publié: (2016)

Live Attenuated Influenza Vaccine Enhances Colonization of <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> and <named-content content-type="genus-species">Staphylococcus aureus</named-content> in Mice
par: Michael J. Mina, et autres
Publié: (2014)

<named-content content-type="genus-species">Bacillus subtilis</named-content> Early Colonization of <named-content content-type="genus-species">Arabidopsis thaliana</named-content> Roots Involves Multiple Chemotaxis Receptors
par: Rosalie Allard-Massicotte, et autres
Publié: (2016)

Peptidoglycan Remodeling Enables <named-content content-type="genus-species">Escherichia</named-content><named-content content-type="genus-species"> coli</named-content> To Survive Severe Outer Membrane Assembly Defect
par: Niccolò Morè, et autres
Publié: (2019)

Transforming the Untransformable: Application of Direct Transformation To Manipulate Genetically <named-content content-type="genus-species">Staphylococcus aureus</named-content> and <named-content content-type="genus-species">Staphylococcus epidermidis</named-content>
par: Ian R. Monk, et autres
Publié: (2012)

Shifting Paradigm on <named-content content-type="genus-species">Bacillus thuringiensis</named-content> Toxin and a Natural Model for <named-content content-type="genus-species">Enterococcus faecalis</named-content> Septicemia
par: Joerg Graf
Publié: (2011)

<named-content content-type="genus-species">Candida albicans</named-content> Impacts <named-content content-type="genus-species">Staphylococcus aureus</named-content> Alpha-Toxin Production via Extracellular Alkalinization
par: Olivia A. Todd, et autres
Publié: (2019)

A <named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Antimicrobial Affects the Biogeography but Not Fitness of <named-content content-type="genus-species">Staphylococcus aureus</named-content> during Coculture
par: Juan P. Barraza, et autres
Publié: (2021)

Exploration of the Biosynthetic Potential of the <italic toggle="yes">Populus</italic> Microbiome
par: Patricia M. Blair, et autres
Publié: (2018)

Inability to Culture <named-content content-type="genus-species">Pneumocystis jirovecii</named-content>
par: Yueqin Liu, et autres
Publié: (2018)

Cytokinin Signaling in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
par: Marie I. Samanovic, et autres
Publié: (2018)

The Genetic Transformation of <named-content content-type="genus-species">Chlamydia pneumoniae</named-content>
par: Kensuke Shima, et autres
Publié: (2018)

<named-content content-type="genus-species">Corynebacterium pseudodiphtheriticum</named-content> Exploits <named-content content-type="genus-species">Staphylococcus aureus</named-content> Virulence Components in a Novel Polymicrobial Defense Strategy
par: Britney L. Hardy, et autres
Publié: (2019)

<named-content content-type="genus-species">Enterococcus faecalis</named-content> Enhances Expression and Activity of the Enterohemorrhagic <named-content content-type="genus-species">Escherichia coli</named-content> Type III Secretion System
par: Elizabeth A. Cameron, et autres
Publié: (2019)

<named-content content-type="genus-species">Pseudomonas aeruginosa</named-content> Increases the Sensitivity of Biofilm-Grown <named-content content-type="genus-species">Staphylococcus aureus</named-content> to Membrane-Targeting Antiseptics and Antibiotics
par: Giulia Orazi, et autres
Publié: (2019)

Unconventional N-Linked Glycosylation Promotes Trimeric Autotransporter Function in <named-content content-type="genus-species">Kingella kingae</named-content> and <named-content content-type="genus-species">Aggregatibacter aphrophilus</named-content>
par: Katherine A. Rempe, et autres
Publié: (2015)

Intravital Imaging Reveals Divergent Cytokine and Cellular Immune Responses to <named-content content-type="genus-species">Candida albicans</named-content> and <named-content content-type="genus-species">Candida parapsilosis</named-content>
par: Linda S. Archambault, et autres
Publié: (2019)