Discovery of the <named-content content-type="genus-species">Pseudomonas</named-content> Polyyne Protegencin by a Phylogeny-Guided Study of Polyyne Biosynthetic Gene Cluster Diversity

ABSTRACT Natural products that possess alkyne or polyyne moieties have been isolated from a variety of biological sources and possess a broad a range of bioactivities. In bacteria, the basic biosynthesis of polyynes is known, but their biosynthetic gene cluster (BGC) distribution and evolutionary re...

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Auteurs principaux: Alex J. Mullins, Gordon Webster, Hak Joong Kim, Jinlian Zhao, Yoana D. Petrova, Christina E. Ramming, Matthew Jenner, James A. H. Murray, Thomas R. Connor, Christian Hertweck, Gregory L. Challis, Eshwar Mahenthiralingam
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
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Accès en ligne:https://doaj.org/article/b1b4253ed1464c9da85b6b1a1b4667c8
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