EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY

We evaluated immunochemical, physical and biochemical properties of Vibrio cholerae 569B INABA protective antigenes, derived on industrial and own-developed bioreactors as well as by technology of its concentration by tangential ultrafiltration. We detected, protease, twinase and. lysophospholipase...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	A. K. Nikiforov, M. N. Kireyev, O. V. Gromova, A. V. Komissarov, S. A. Yeriomin, O. A. Volokh, Yu. A. Aleshina, A. V. Gayeva, T. L. Zakharova, V. I. Pavlova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	vibrio cholerae cholerogen-anatoxine o-antigen features Science Q
Acceso en línea:	https://doaj.org/article/b1b9b3cdfb5c45649dad965ca76841bd
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b1b9b3cdfb5c45649dad965ca76841bd
record_format	dspace
spelling	oai:doaj.org-article:b1b9b3cdfb5c45649dad965ca76841bd2021-11-23T06:14:24ZEVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY2541-94202587-9596https://doaj.org/article/b1b9b3cdfb5c45649dad965ca76841bd2012-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1149https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596We evaluated immunochemical, physical and biochemical properties of Vibrio cholerae 569B INABA protective antigenes, derived on industrial and own-developed bioreactors as well as by technology of its concentration by tangential ultrafiltration. We detected, protease, twinase and. lysophospholipase in all samples. Also, dotimmunoanalysis showed equal concentration, of cholerogen-anatoxine and. O-antigen in all samples too. Using chromatography and. electrophoresis, we found their properties as similar. Thus, we suppose to be possible using developed bioreactor as well as technology of Vibrio cholerae 569B INABA protective antigens concentration by tangential concentration during a process of synthetic oral cholera vaccine production.A. K. NikiforovM. N. KireyevO. V. GromovaA. V. KomissarovS. A. YeriominO. A. VolokhYu. A. AleshinaA. V. GayevaT. L. ZakharovaV. I. PavlovaScientific Сentre for Family Health and Human Reproduction Problemsarticlevibrio choleraecholerogen-anatoxineo-antigenfeaturesvibrio choleraeScienceQRUActa Biomedica Scientifica, Vol 0, Iss 5(1), Pp 284-287 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	vibrio cholerae cholerogen-anatoxine o-antigen features vibrio cholerae Science Q
spellingShingle	vibrio cholerae cholerogen-anatoxine o-antigen features vibrio cholerae Science Q A. K. Nikiforov M. N. Kireyev O. V. Gromova A. V. Komissarov S. A. Yeriomin O. A. Volokh Yu. A. Aleshina A. V. Gayeva T. L. Zakharova V. I. Pavlova EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
description	We evaluated immunochemical, physical and biochemical properties of Vibrio cholerae 569B INABA protective antigenes, derived on industrial and own-developed bioreactors as well as by technology of its concentration by tangential ultrafiltration. We detected, protease, twinase and. lysophospholipase in all samples. Also, dotimmunoanalysis showed equal concentration, of cholerogen-anatoxine and. O-antigen in all samples too. Using chromatography and. electrophoresis, we found their properties as similar. Thus, we suppose to be possible using developed bioreactor as well as technology of Vibrio cholerae 569B INABA protective antigens concentration by tangential concentration during a process of synthetic oral cholera vaccine production.
format	article
author	A. K. Nikiforov M. N. Kireyev O. V. Gromova A. V. Komissarov S. A. Yeriomin O. A. Volokh Yu. A. Aleshina A. V. Gayeva T. L. Zakharova V. I. Pavlova
author_facet	A. K. Nikiforov M. N. Kireyev O. V. Gromova A. V. Komissarov S. A. Yeriomin O. A. Volokh Yu. A. Aleshina A. V. Gayeva T. L. Zakharova V. I. Pavlova
author_sort	A. K. Nikiforov
title	EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
title_short	EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
title_full	EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
title_fullStr	EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
title_full_unstemmed	EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY
title_sort	evaluation of vibrio cholerae 569b inaba protective antigenes, derived on industrial and developed bioreactors as well as by improved technology
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/b1b9b3cdfb5c45649dad965ca76841bd
work_keys_str_mv	AT aknikiforov evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT mnkireyev evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT ovgromova evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT avkomissarov evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT sayeriomin evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT oavolokh evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT yuaaleshina evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT avgayeva evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT tlzakharova evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology AT vipavlova evaluationofvibriocholerae569binabaprotectiveantigenesderivedonindustrialanddevelopedbioreactorsaswellasbyimprovedtechnology
_version_	1718417215410143232

EVALUATION OF VIBRIO CHOLERAE 569B INABA PROTECTIVE ANTIGENES, DERIVED ON INDUSTRIAL AND DEVELOPED BIOREACTORS AS WELL AS BY IMPROVED TECHNOLOGY

Ejemplares similares