Identification, replication and characterization of epigenetic remodelling in the aging genome: a cross population analysis

Abstract Aging is a complex biological process regulated by multiple cellular pathways and molecular mechanisms including epigenetics. Using genome-wide DNA methylation data measured in a large collection of Scottish old individuals, we performed discovery association analysis to identify age-methyl...

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Auteurs principaux: Shuxia Li, Lene Christiansen, Kaare Christensen, Torben A. Kruse, Paul Redmond, Riccardo E. Marioni, Ian J. Deary, Qihua Tan
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/b1bb2d7ea93c4e6193b7d93d4213dc62
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