Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.

Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.

Obesity is an underlying risk factor in the development of cardiovascular disease, dyslipidemia and non-alcoholic fatty liver disease (NAFLD). Increased hepatic lipid accumulation is a hallmark in the progression of NAFLD and impairments in liver phosphatidylcholine (PC) metabolism may be central to...

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Autores principales: Christoph Dahlhoff, Charles Desmarchelier, Manuela Sailer, Rainer W Fürst, Alexander Haag, Susanne E Ulbrich, Björn Hummel, Rima Obeid, Jürgen Geisel, Bernhard L Bader, Hannelore Daniel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/b1bdba7ee80a47a8aecdb10c3b4e2918
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