Expression and purification of functional recombinant CUL2•RBX1 from E. coli

Abstract Cullin-2 (CUL2) based cullin-RING ligases (CRL2s) comprise a family of ubiquitin E3 ligases that exist only in multi-cellular organisms and are crucial for cellular processes such as embryogenesis and viral pathogenesis. CUL2 is the scaffold protein that binds one of the interchangeable sub...

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Autores principales: Stephanie Diaz, Lihong Li, Kankan Wang, Xing Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b1c3ddfa0b8b499594be9428b726f52b
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