Expression and purification of functional recombinant CUL2•RBX1 from E. coli
Abstract Cullin-2 (CUL2) based cullin-RING ligases (CRL2s) comprise a family of ubiquitin E3 ligases that exist only in multi-cellular organisms and are crucial for cellular processes such as embryogenesis and viral pathogenesis. CUL2 is the scaffold protein that binds one of the interchangeable sub...
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Main Authors: | Stephanie Diaz, Lihong Li, Kankan Wang, Xing Liu |
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Format: | article |
Language: | EN |
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Nature Portfolio
2021
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Online Access: | https://doaj.org/article/b1c3ddfa0b8b499594be9428b726f52b |
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