Hormonal Approach for Postmenopausal Vulvovaginal Atrophy

Menopause is a physiological and progressive phenomenon secondary to decreased ovarian follicular reserve that significantly affects the genital tract. Although postmenopausal vulvovaginal atrophy primarily affects postmenopausal women, it is also seen in premenopausal women. The hypoestrogenic cond...

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Autores principales: Ana Paula Ferreira Costa, Ayane Cristine Alves Sarmento, Pedro Vieira-Baptista, José Eleutério, Ricardo Ney Cobucci, Ana Katherine Gonçalves
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Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/b1cdcdff0ff94a3493ddce814ad69de0
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spelling oai:doaj.org-article:b1cdcdff0ff94a3493ddce814ad69de02021-12-01T14:11:57ZHormonal Approach for Postmenopausal Vulvovaginal Atrophy2673-315310.3389/frph.2021.783247https://doaj.org/article/b1cdcdff0ff94a3493ddce814ad69de02021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/frph.2021.783247/fullhttps://doaj.org/toc/2673-3153Menopause is a physiological and progressive phenomenon secondary to decreased ovarian follicular reserve that significantly affects the genital tract. Although postmenopausal vulvovaginal atrophy primarily affects postmenopausal women, it is also seen in premenopausal women. The hypoestrogenic condition results in hormonal and anatomical changes, with the main symptoms, are dryness, burning and genital irritation, decreased lubrication, urinary urgency, dysuria, and recurrent urinary tract infections. This review aims to update hormone therapy for urogenital atrophy, both local and systemic, and discusses the importance of understanding and the need for active treatment of this condition. The main therapeutic objective is the relief of symptoms, and hormonal therapy (HT) is still the most effective choice for treating clinical manifestations, despite the side effects of its use. HT should be used in an individualized way to the needs of the women and appropriate to the stage in which she is menopausal, perimenopausal, or after menopause.Ana Paula Ferreira CostaAyane Cristine Alves SarmentoPedro Vieira-BaptistaPedro Vieira-BaptistaJosé EleutérioRicardo Ney CobucciAna Katherine GonçalvesAna Katherine GonçalvesFrontiers Media S.A.articlemenopausevulvovaginal atrophyhormone therapyestrogenDHEAtestosteroneReproductionQH471-489Medicine (General)R5-920ENFrontiers in Reproductive Health, Vol 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic menopause
vulvovaginal atrophy
hormone therapy
estrogen
DHEA
testosterone
Reproduction
QH471-489
Medicine (General)
R5-920
spellingShingle menopause
vulvovaginal atrophy
hormone therapy
estrogen
DHEA
testosterone
Reproduction
QH471-489
Medicine (General)
R5-920
Ana Paula Ferreira Costa
Ayane Cristine Alves Sarmento
Pedro Vieira-Baptista
Pedro Vieira-Baptista
José Eleutério
Ricardo Ney Cobucci
Ana Katherine Gonçalves
Ana Katherine Gonçalves
Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
description Menopause is a physiological and progressive phenomenon secondary to decreased ovarian follicular reserve that significantly affects the genital tract. Although postmenopausal vulvovaginal atrophy primarily affects postmenopausal women, it is also seen in premenopausal women. The hypoestrogenic condition results in hormonal and anatomical changes, with the main symptoms, are dryness, burning and genital irritation, decreased lubrication, urinary urgency, dysuria, and recurrent urinary tract infections. This review aims to update hormone therapy for urogenital atrophy, both local and systemic, and discusses the importance of understanding and the need for active treatment of this condition. The main therapeutic objective is the relief of symptoms, and hormonal therapy (HT) is still the most effective choice for treating clinical manifestations, despite the side effects of its use. HT should be used in an individualized way to the needs of the women and appropriate to the stage in which she is menopausal, perimenopausal, or after menopause.
format article
author Ana Paula Ferreira Costa
Ayane Cristine Alves Sarmento
Pedro Vieira-Baptista
Pedro Vieira-Baptista
José Eleutério
Ricardo Ney Cobucci
Ana Katherine Gonçalves
Ana Katherine Gonçalves
author_facet Ana Paula Ferreira Costa
Ayane Cristine Alves Sarmento
Pedro Vieira-Baptista
Pedro Vieira-Baptista
José Eleutério
Ricardo Ney Cobucci
Ana Katherine Gonçalves
Ana Katherine Gonçalves
author_sort Ana Paula Ferreira Costa
title Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
title_short Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
title_full Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
title_fullStr Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
title_full_unstemmed Hormonal Approach for Postmenopausal Vulvovaginal Atrophy
title_sort hormonal approach for postmenopausal vulvovaginal atrophy
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/b1cdcdff0ff94a3493ddce814ad69de0
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