Engineered HSV vector achieves safe long-term transgene expression in the central nervous system
Abstract Previously we reported a new series of highly defective herpes simplex virus type 1 (HSV-1) vectors that were functionally devoid of all viral immediately early (IE) genes, resulting in virtual absence of viral gene expression. Nevertheless, a reporter gene cassette inserted into the vector...
Guardado en:
Autores principales: | Gianluca Verlengia, Yoshitaka Miyagawa, Selene Ingusci, Justus B. Cohen, Michele Simonato, Joseph C. Glorioso |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b1d3758c4d1a4cf094352f0ec281ebd2 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Delivery of large transgene cassettes by foamy virus vector
por: Nathan Paul Sweeney, et al.
Publicado: (2017) -
Enhancing titres of therapeutic viral vectors using the transgene repression in vector production (TRiP) system
por: H. E. Maunder, et al.
Publicado: (2017) -
Blood meal-induced inhibition of vector-borne disease by transgenic microbiota
por: Jackie L. Shane, et al.
Publicado: (2018) -
Molecular engineering of safe and efficacious oral basal insulin
por: Frantisek Hubálek, et al.
Publicado: (2020) -
Transgenic quail production by microinjection of lentiviral vector into the early embryo blood vessels.
por: Zifu Zhang, et al.
Publicado: (2012)