TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread

Controlled cell death can be an efficient anti-viral strategy, but also leads to tissue damage and needs to be balanced. Oyler-Yaniv et al. combine mathematical modelling and microscopy to show that exposure to TNF in response to viral infection causes cells to tune their speed-vs-accuracy trade-off...

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Autores principales:	Jennifer Oyler-Yaniv, Alon Oyler-Yaniv, Evan Maltz, Roy Wollman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b1d41722ca9e4de692d6e4d06caafe69
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spelling	oai:doaj.org-article:b1d41722ca9e4de692d6e4d06caafe692021-12-02T14:58:51ZTNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread10.1038/s41467-021-23195-92041-1723https://doaj.org/article/b1d41722ca9e4de692d6e4d06caafe692021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23195-9https://doaj.org/toc/2041-1723Controlled cell death can be an efficient anti-viral strategy, but also leads to tissue damage and needs to be balanced. Oyler-Yaniv et al. combine mathematical modelling and microscopy to show that exposure to TNF in response to viral infection causes cells to tune their speed-vs-accuracy trade-off in cell death decision to limit HSV-1 spread.Jennifer Oyler-YanivAlon Oyler-YanivEvan MaltzRoy WollmanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jennifer Oyler-Yaniv Alon Oyler-Yaniv Evan Maltz Roy Wollman TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
description	Controlled cell death can be an efficient anti-viral strategy, but also leads to tissue damage and needs to be balanced. Oyler-Yaniv et al. combine mathematical modelling and microscopy to show that exposure to TNF in response to viral infection causes cells to tune their speed-vs-accuracy trade-off in cell death decision to limit HSV-1 spread.
format	article
author	Jennifer Oyler-Yaniv Alon Oyler-Yaniv Evan Maltz Roy Wollman
author_facet	Jennifer Oyler-Yaniv Alon Oyler-Yaniv Evan Maltz Roy Wollman
author_sort	Jennifer Oyler-Yaniv
title	TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
title_short	TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
title_full	TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
title_fullStr	TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
title_full_unstemmed	TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
title_sort	tnf controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b1d41722ca9e4de692d6e4d06caafe69
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TNF controls a speed-accuracy tradeoff in the cell death decision to restrict viral spread

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