Inducement of experimental Abdominal Adhesions (literature review)

Adhesive disease of the abdominal cavity is a common medical problem that impairs the patients’ life quality. Adhesive intestinal obstruction ranks first in the structure of acute bowel obstruction. The levels of complications and postoperative mortality are not likely to decrease. Consequently, the...

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Autores principales: N. I. Ayushinova, I. A. Shurygina, E. G. Grigoriev, M. G. Shurygin
Formato: article
Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2019
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Acceso en línea:https://doaj.org/article/b1e243f4823543f1acdcf6769f5ae7f0
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spelling oai:doaj.org-article:b1e243f4823543f1acdcf6769f5ae7f02021-11-23T06:14:41ZInducement of experimental Abdominal Adhesions (literature review)2541-94202587-959610.29413/ABS.2018-3.6.15https://doaj.org/article/b1e243f4823543f1acdcf6769f5ae7f02019-01-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1872https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Adhesive disease of the abdominal cavity is a common medical problem that impairs the patients’ life quality. Adhesive intestinal obstruction ranks first in the structure of acute bowel obstruction. The levels of complications and postoperative mortality are not likely to decrease. Consequently, the studies on preventing adhesive disease are still in progress, which requires an animal model to induce abdominal adhesive process. Numerous factors of peritoneum injury result in adhesion formation. Experimental surgery offers various techniques of inducing the adhesive process in the abdominal cavity based on mechanical, chemical, biological, implantation injury factors. Recent trends in intra-abdominal adhesion stimulation are designed to approximate at maximum an animal model and present surgical and gynecologic procedures. In the review article, we survey and systematize different ways of inducing intra-abdominal adhesive process with various injury factors. The choice of study animal, the ways of peritoneum injury, followed by septic or aseptic inflammation are analyzed. The rating scales for the severity of adhesive process are also organized and compared. The number of existing models is large which is evident of the outstanding problem and promising outlook of scientific research.N. I. AyushinovaI. A. ShuryginaE. G. GrigorievM. G. ShuryginScientific Сentre for Family Health and Human Reproduction Problemsarticleadhesionsabdominal cavityexperimentmodelScienceQRUActa Biomedica Scientifica, Vol 3, Iss 6, Pp 107-113 (2019)
institution DOAJ
collection DOAJ
language RU
topic adhesions
abdominal cavity
experiment
model
Science
Q
spellingShingle adhesions
abdominal cavity
experiment
model
Science
Q
N. I. Ayushinova
I. A. Shurygina
E. G. Grigoriev
M. G. Shurygin
Inducement of experimental Abdominal Adhesions (literature review)
description Adhesive disease of the abdominal cavity is a common medical problem that impairs the patients’ life quality. Adhesive intestinal obstruction ranks first in the structure of acute bowel obstruction. The levels of complications and postoperative mortality are not likely to decrease. Consequently, the studies on preventing adhesive disease are still in progress, which requires an animal model to induce abdominal adhesive process. Numerous factors of peritoneum injury result in adhesion formation. Experimental surgery offers various techniques of inducing the adhesive process in the abdominal cavity based on mechanical, chemical, biological, implantation injury factors. Recent trends in intra-abdominal adhesion stimulation are designed to approximate at maximum an animal model and present surgical and gynecologic procedures. In the review article, we survey and systematize different ways of inducing intra-abdominal adhesive process with various injury factors. The choice of study animal, the ways of peritoneum injury, followed by septic or aseptic inflammation are analyzed. The rating scales for the severity of adhesive process are also organized and compared. The number of existing models is large which is evident of the outstanding problem and promising outlook of scientific research.
format article
author N. I. Ayushinova
I. A. Shurygina
E. G. Grigoriev
M. G. Shurygin
author_facet N. I. Ayushinova
I. A. Shurygina
E. G. Grigoriev
M. G. Shurygin
author_sort N. I. Ayushinova
title Inducement of experimental Abdominal Adhesions (literature review)
title_short Inducement of experimental Abdominal Adhesions (literature review)
title_full Inducement of experimental Abdominal Adhesions (literature review)
title_fullStr Inducement of experimental Abdominal Adhesions (literature review)
title_full_unstemmed Inducement of experimental Abdominal Adhesions (literature review)
title_sort inducement of experimental abdominal adhesions (literature review)
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2019
url https://doaj.org/article/b1e243f4823543f1acdcf6769f5ae7f0
work_keys_str_mv AT niayushinova inducementofexperimentalabdominaladhesionsliteraturereview
AT iashurygina inducementofexperimentalabdominaladhesionsliteraturereview
AT eggrigoriev inducementofexperimentalabdominaladhesionsliteraturereview
AT mgshurygin inducementofexperimentalabdominaladhesionsliteraturereview
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