Brain-targeted drug delivery by manipulating protein corona functions

Plasma proteins may severely affect the in vivo performance of liposomes. Here, the authors develop bio-inspired liposomes that specifically absorb brain-targeted apolipoproteins and preserve their bioactivities, thereby achieving efficient brain targeting with minor influence on immunocompatibility...

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Autores principales: Zui Zhang, Juan Guan, Zhuxuan Jiang, Yang Yang, Jican Liu, Wei Hua, Ying Mao, Cheng Li, Weiyue Lu, Jun Qian, Changyou Zhan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/b1ea7b0d338d4e65ab52310d8be62181
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