Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix

Abstract MR Radiomics based on cervical lesions from one single scanner has achieved promising results. However, it is a challenge to achieve clinical translation. Considering multi-scanners and non-uniform scanning parameters from different centers in a real-world medical scenario, we should first...

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Autores principales:	Honglan Mi, Mingyuan Yuan, Shiteng Suo, Jiejun Cheng, Suqin Li, Shaofeng Duan, Qing Lu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b1ecb24fe431496893126be9adb09656
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spelling	oai:doaj.org-article:b1ecb24fe431496893126be9adb096562021-12-02T15:10:11ZImpact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix10.1038/s41598-020-76989-02045-2322https://doaj.org/article/b1ecb24fe431496893126be9adb096562020-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-76989-0https://doaj.org/toc/2045-2322Abstract MR Radiomics based on cervical lesions from one single scanner has achieved promising results. However, it is a challenge to achieve clinical translation. Considering multi-scanners and non-uniform scanning parameters from different centers in a real-world medical scenario, we should first identify the influence of such conditions on the robustness of MR radiomics features (RFs) based on the female cervix. In this study, 9 healthy female volunteers were enrolled and 3 kiwis were selected as references. Each of them underwent T2 weighted imaging in three different 3.0-T MR scanners with uniform acquisition parameters, and in one MR scanner with various scanning parameters. A total of 396 RFs were extracted from their images with and without decile intensity normalization. The RFs’ reproducibility was evaluated by coefficient of variation (CV) and quartile coefficient of dispersion (QCD). Representative features were selected using the hierarchical cluster analysis and their discrimination abilities were estimated by ROC analysis through retrospective comparison with the junctional zone and the outer muscular layer of healthy cervix in patients (n = 58) with leiomyoma. This study showed that only a few RFs were robust across different MR scanners and acquisition parameters based on females’ cervix, which might be improved by decile intensity normalization method.Honglan MiMingyuan YuanShiteng SuoJiejun ChengSuqin LiShaofeng DuanQing LuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Honglan Mi Mingyuan Yuan Shiteng Suo Jiejun Cheng Suqin Li Shaofeng Duan Qing Lu Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
description	Abstract MR Radiomics based on cervical lesions from one single scanner has achieved promising results. However, it is a challenge to achieve clinical translation. Considering multi-scanners and non-uniform scanning parameters from different centers in a real-world medical scenario, we should first identify the influence of such conditions on the robustness of MR radiomics features (RFs) based on the female cervix. In this study, 9 healthy female volunteers were enrolled and 3 kiwis were selected as references. Each of them underwent T2 weighted imaging in three different 3.0-T MR scanners with uniform acquisition parameters, and in one MR scanner with various scanning parameters. A total of 396 RFs were extracted from their images with and without decile intensity normalization. The RFs’ reproducibility was evaluated by coefficient of variation (CV) and quartile coefficient of dispersion (QCD). Representative features were selected using the hierarchical cluster analysis and their discrimination abilities were estimated by ROC analysis through retrospective comparison with the junctional zone and the outer muscular layer of healthy cervix in patients (n = 58) with leiomyoma. This study showed that only a few RFs were robust across different MR scanners and acquisition parameters based on females’ cervix, which might be improved by decile intensity normalization method.
format	article
author	Honglan Mi Mingyuan Yuan Shiteng Suo Jiejun Cheng Suqin Li Shaofeng Duan Qing Lu
author_facet	Honglan Mi Mingyuan Yuan Shiteng Suo Jiejun Cheng Suqin Li Shaofeng Duan Qing Lu
author_sort	Honglan Mi
title	Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
title_short	Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
title_full	Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
title_fullStr	Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
title_full_unstemmed	Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix
title_sort	impact of different scanners and acquisition parameters on robustness of mr radiomics features based on women’s cervix
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b1ecb24fe431496893126be9adb09656
work_keys_str_mv	AT honglanmi impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT mingyuanyuan impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT shitengsuo impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT jiejuncheng impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT suqinli impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT shaofengduan impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix AT qinglu impactofdifferentscannersandacquisitionparametersonrobustnessofmrradiomicsfeaturesbasedonwomenscervix
_version_	1718387712574095360

Impact of different scanners and acquisition parameters on robustness of MR radiomics features based on women’s cervix

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