Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titers in the saliva of vaccinees suggest that transmis...

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Autores principales:	Matthias Becker, Alex Dulovic, Daniel Junker, Natalia Ruetalo, Philipp D. Kaiser, Yudi T. Pinilla, Constanze Heinzel, Julia Haering, Bjoern Traenkle, Teresa R. Wagner, Mirjam Layer, Martin Mehrlaender, Valbona Mirakaj, Jana Held, Hannes Planatscher, Katja Schenke-Layland, Gérard Krause, Monika Strengert, Tamam Bakchoul, Karina Althaus, Rolf Fendel, Andrea Kreidenweiss, Michael Koeppen, Ulrich Rothbauer, Michael Schindler, Nicole Schneiderhan-Marra
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b1f0cfb4a3c942a594406b501e462f7e
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spelling	oai:doaj.org-article:b1f0cfb4a3c942a594406b501e462f7e2021-12-02T15:00:49ZImmune response to SARS-CoV-2 variants of concern in vaccinated individuals10.1038/s41467-021-23473-62041-1723https://doaj.org/article/b1f0cfb4a3c942a594406b501e462f7e2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23473-6https://doaj.org/toc/2041-1723Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titers in the saliva of vaccinees suggest that transmission may be reduced.Matthias BeckerAlex DulovicDaniel JunkerNatalia RuetaloPhilipp D. KaiserYudi T. PinillaConstanze HeinzelJulia HaeringBjoern TraenkleTeresa R. WagnerMirjam LayerMartin MehrlaenderValbona MirakajJana HeldHannes PlanatscherKatja Schenke-LaylandGérard KrauseMonika StrengertTamam BakchoulKarina AlthausRolf FendelAndrea KreidenweissMichael KoeppenUlrich RothbauerMichael SchindlerNicole Schneiderhan-MarraNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Matthias Becker Alex Dulovic Daniel Junker Natalia Ruetalo Philipp D. Kaiser Yudi T. Pinilla Constanze Heinzel Julia Haering Bjoern Traenkle Teresa R. Wagner Mirjam Layer Martin Mehrlaender Valbona Mirakaj Jana Held Hannes Planatscher Katja Schenke-Layland Gérard Krause Monika Strengert Tamam Bakchoul Karina Althaus Rolf Fendel Andrea Kreidenweiss Michael Koeppen Ulrich Rothbauer Michael Schindler Nicole Schneiderhan-Marra Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
description	Here, the authors characterize the antibody response from vaccinated (Pfizer BNT-162b2), infected and uninfected individuals against emerging variants of concern of SARS-CoV-2, finding reduced neutralization of a South African isolate. High IgG titers in the saliva of vaccinees suggest that transmission may be reduced.
format	article
author	Matthias Becker Alex Dulovic Daniel Junker Natalia Ruetalo Philipp D. Kaiser Yudi T. Pinilla Constanze Heinzel Julia Haering Bjoern Traenkle Teresa R. Wagner Mirjam Layer Martin Mehrlaender Valbona Mirakaj Jana Held Hannes Planatscher Katja Schenke-Layland Gérard Krause Monika Strengert Tamam Bakchoul Karina Althaus Rolf Fendel Andrea Kreidenweiss Michael Koeppen Ulrich Rothbauer Michael Schindler Nicole Schneiderhan-Marra
author_facet	Matthias Becker Alex Dulovic Daniel Junker Natalia Ruetalo Philipp D. Kaiser Yudi T. Pinilla Constanze Heinzel Julia Haering Bjoern Traenkle Teresa R. Wagner Mirjam Layer Martin Mehrlaender Valbona Mirakaj Jana Held Hannes Planatscher Katja Schenke-Layland Gérard Krause Monika Strengert Tamam Bakchoul Karina Althaus Rolf Fendel Andrea Kreidenweiss Michael Koeppen Ulrich Rothbauer Michael Schindler Nicole Schneiderhan-Marra
author_sort	Matthias Becker
title	Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
title_short	Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
title_full	Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
title_fullStr	Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
title_full_unstemmed	Immune response to SARS-CoV-2 variants of concern in vaccinated individuals
title_sort	immune response to sars-cov-2 variants of concern in vaccinated individuals
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b1f0cfb4a3c942a594406b501e462f7e
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Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

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