Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract

Purpose. The previous lab and clinical studies of the correlation between the ultraviolet B and age-related cataract (ARC) did not reach in the universal agreement, especially in different morphological types of ARC. It is important to systemically summarize those previous data of epidemiological st...

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Autores principales:	Xiaochun Li, Xiaoguang Cao, Yingying Yu, Yongzhen Bao
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/b1f12b587335443fb55f50ecd9ac3208
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spelling	oai:doaj.org-article:b1f12b587335443fb55f50ecd9ac32082021-11-22T01:11:34ZCorrelation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract2314-614110.1155/2021/8748463https://doaj.org/article/b1f12b587335443fb55f50ecd9ac32082021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/8748463https://doaj.org/toc/2314-6141Purpose. The previous lab and clinical studies of the correlation between the ultraviolet B and age-related cataract (ARC) did not reach in the universal agreement, especially in different morphological types of ARC. It is important to systemically summarize those previous data of epidemiological studies, which might penetrate the relevance between three morphological types of ARC, cortical, nuclear, and posterior capsular (PSC), with sunlight exposure. Methods. PubMed, Web of Science, CNKI, Embase, and Cochrane were searched online. Data were extracted and recalculated, and quality check was performed by hand. Review Manager was used to perform the fixed effects meta-analysis on ARC and its morphological types. The highest exposed dose group was defined as the exposed group, and the lowest dose group as the control group as possible. Results. Finally, the number of analyzed studies was 31: 20 for ARC and twelve, eleven, and nine for the morphological types cortical, nuclear, and PSC, respectively. The pooled OR for ARC was 1.15 (range 1.00~43.78, 95% CI 1.09 to 1.21). The cortical cataract revealed a slightly higher risk, and pooled OR was 1.03 (range 0.67~2.91, 95% CI 1.02 to 1.03). But the pooled OR for nuclear and PSC were 1.00 (range 0.50~5.35, 95% CI 1.00 to 1.00) and 0.99 (range 0.57~1.87, 95% CI 0.95 to 1.01), respectively. Conclusions. The systemic analysis of epidemiological articles reported till now reveals a significantly increased risk of ARC for those exposed with more sunlight, especially the morphological type of cortical cataract.Xiaochun LiXiaoguang CaoYingying YuYongzhen BaoHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Xiaochun Li Xiaoguang Cao Yingying Yu Yongzhen Bao Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
description	Purpose. The previous lab and clinical studies of the correlation between the ultraviolet B and age-related cataract (ARC) did not reach in the universal agreement, especially in different morphological types of ARC. It is important to systemically summarize those previous data of epidemiological studies, which might penetrate the relevance between three morphological types of ARC, cortical, nuclear, and posterior capsular (PSC), with sunlight exposure. Methods. PubMed, Web of Science, CNKI, Embase, and Cochrane were searched online. Data were extracted and recalculated, and quality check was performed by hand. Review Manager was used to perform the fixed effects meta-analysis on ARC and its morphological types. The highest exposed dose group was defined as the exposed group, and the lowest dose group as the control group as possible. Results. Finally, the number of analyzed studies was 31: 20 for ARC and twelve, eleven, and nine for the morphological types cortical, nuclear, and PSC, respectively. The pooled OR for ARC was 1.15 (range 1.00~43.78, 95% CI 1.09 to 1.21). The cortical cataract revealed a slightly higher risk, and pooled OR was 1.03 (range 0.67~2.91, 95% CI 1.02 to 1.03). But the pooled OR for nuclear and PSC were 1.00 (range 0.50~5.35, 95% CI 1.00 to 1.00) and 0.99 (range 0.57~1.87, 95% CI 0.95 to 1.01), respectively. Conclusions. The systemic analysis of epidemiological articles reported till now reveals a significantly increased risk of ARC for those exposed with more sunlight, especially the morphological type of cortical cataract.
format	article
author	Xiaochun Li Xiaoguang Cao Yingying Yu Yongzhen Bao
author_facet	Xiaochun Li Xiaoguang Cao Yingying Yu Yongzhen Bao
author_sort	Xiaochun Li
title	Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
title_short	Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
title_full	Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
title_fullStr	Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
title_full_unstemmed	Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract
title_sort	correlation of sunlight exposure and different morphological types of age-related cataract
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/b1f12b587335443fb55f50ecd9ac3208
work_keys_str_mv	AT xiaochunli correlationofsunlightexposureanddifferentmorphologicaltypesofagerelatedcataract AT xiaoguangcao correlationofsunlightexposureanddifferentmorphologicaltypesofagerelatedcataract AT yingyingyu correlationofsunlightexposureanddifferentmorphologicaltypesofagerelatedcataract AT yongzhenbao correlationofsunlightexposureanddifferentmorphologicaltypesofagerelatedcataract
_version_	1718418300942155776

Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract

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