Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum.

Reduced tissue perfusion leading to tissue ischemia is a central component of the pathogenesis of myonecrosis caused by Clostridium perfringens. The C. perfringens alpha-toxin has been shown capable of inducing these changes, but its potential synergy with perfringolysin O (theta-toxin) is less well...

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Autores principales: Michael J Hickey, Rain Y Q Kwan, Milena M Awad, Catherine L Kennedy, Lauren F Young, Pam Hall, Leanne M Cordner, Dena Lyras, John J Emmins, Julian I Rood
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/b20197b5218e4ca4ace2e83cf9b275b5
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