Molecular and cellular basis of microvascular perfusion deficits induced by Clostridium perfringens and Clostridium septicum.
Reduced tissue perfusion leading to tissue ischemia is a central component of the pathogenesis of myonecrosis caused by Clostridium perfringens. The C. perfringens alpha-toxin has been shown capable of inducing these changes, but its potential synergy with perfringolysin O (theta-toxin) is less well...
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Autores principales: | Michael J Hickey, Rain Y Q Kwan, Milena M Awad, Catherine L Kennedy, Lauren F Young, Pam Hall, Leanne M Cordner, Dena Lyras, John J Emmins, Julian I Rood |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2008
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Materias: | |
Acceso en línea: | https://doaj.org/article/b20197b5218e4ca4ace2e83cf9b275b5 |
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