Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

Objectives:. Coronavirus disease 2019 is caused by the novel severe acute respiratory syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular thrombosis, which may contribute to mortality. Our aim was to profile plasma thrombotic factors and endothelial injury markers in...

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Main Authors: Douglas D. Fraser, MD, PhD, Eric K. Patterson, PhD, Marat Slessarev, MD, MSc, Sean E. Gill, PhD, Claudio Martin, MD, MSc, Mark Daley, PhD, Michael R. Miller, PhD, Maitray A. Patel, BSc, Claudia C. dos Santos, MD, MSc, Karen J. Bosma, MD, David B. O’Gorman, PhD, Gediminas Cepinskas, DVM, PhD, on behalf of the Lawson COVID19 Study Team, Robert Arntfield, Ian Ball, Gordon Barkwell, Tracey Bentall, Karen Bosma, Saoirse Cameron, Eileen Campbell, David Carter, Carolina Gillio-Meina, Robert Hegele, Natalya Odoardi, Ram Singh, Kelly Summers, Sue Tereschyn
Format: article
Language:EN
Published: Wolters Kluwer 2020
Subjects:
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Online Access:https://doaj.org/article/b201f1567225428ab5d1671023780bbd
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https://doaj.org/article/b201f1567225428ab5d1671023780bbd

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