Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress

Intrauterine growth restriction is associated with increased risk for chronic diseases in adults. Here the authors identify fetuin-A as a HIF target gene and describe its protective role in the kidney, counteracting disease mechanisms such as calcification, macrophage polarization, and fibrosis.

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Autores principales: Stefan Rudloff, Mathilde Janot, Stephane Rodriguez, Kevin Dessalle, Willi Jahnen-Dechent, Uyen Huynh-Do
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b20321b21d3a4a83a7ef31a0fb9d941a
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spelling oai:doaj.org-article:b20321b21d3a4a83a7ef31a0fb9d941a2021-12-02T14:18:55ZFetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress10.1038/s41467-020-20832-72041-1723https://doaj.org/article/b20321b21d3a4a83a7ef31a0fb9d941a2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20832-7https://doaj.org/toc/2041-1723Intrauterine growth restriction is associated with increased risk for chronic diseases in adults. Here the authors identify fetuin-A as a HIF target gene and describe its protective role in the kidney, counteracting disease mechanisms such as calcification, macrophage polarization, and fibrosis.Stefan RudloffMathilde JanotStephane RodriguezKevin DessalleWilli Jahnen-DechentUyen Huynh-DoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefan Rudloff
Mathilde Janot
Stephane Rodriguez
Kevin Dessalle
Willi Jahnen-Dechent
Uyen Huynh-Do
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
description Intrauterine growth restriction is associated with increased risk for chronic diseases in adults. Here the authors identify fetuin-A as a HIF target gene and describe its protective role in the kidney, counteracting disease mechanisms such as calcification, macrophage polarization, and fibrosis.
format article
author Stefan Rudloff
Mathilde Janot
Stephane Rodriguez
Kevin Dessalle
Willi Jahnen-Dechent
Uyen Huynh-Do
author_facet Stefan Rudloff
Mathilde Janot
Stephane Rodriguez
Kevin Dessalle
Willi Jahnen-Dechent
Uyen Huynh-Do
author_sort Stefan Rudloff
title Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
title_short Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
title_full Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
title_fullStr Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
title_full_unstemmed Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
title_sort fetuin-a is a hif target that safeguards tissue integrity during hypoxic stress
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b20321b21d3a4a83a7ef31a0fb9d941a
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