Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing

Abstract We xeno-transplanted human neural precursor cells derived from induced pluripotent stem cells into the cerebellum and brainstem of mice and rats during prenatal development or the first postnatal week. The transplants survived and started to differentiate up to 1 month after birth when they...

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Autores principales: Giulia Nato, Alessandro Corti, Elena Parmigiani, Elena Jachetti, Daniele Lecis, Mario Paolo Colombo, Domenico Delia, Annalisa Buffo, Lorenzo Magrassi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b218f6be9a034a4a967efb0818500804
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