Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain

Bacterial chemoreceptors have multiple methylation sites, but whether the order of methylation matters is unclear. Here, the authors show that sequentially ordered methylation is critical for perfect adaptation and for attenuating the trade-off between accurate adaptation and high response gain.

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Detalles Bibliográficos
Autores principales:	Bernardo A. Mello, Anderson B. Beserra, Yuhai Tu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b2276006704844bcbbc28291af6c48e2
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spelling	oai:doaj.org-article:b2276006704844bcbbc28291af6c48e22021-12-02T17:47:17ZSequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain10.1038/s41467-020-16644-42041-1723https://doaj.org/article/b2276006704844bcbbc28291af6c48e22020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16644-4https://doaj.org/toc/2041-1723Bacterial chemoreceptors have multiple methylation sites, but whether the order of methylation matters is unclear. Here, the authors show that sequentially ordered methylation is critical for perfect adaptation and for attenuating the trade-off between accurate adaptation and high response gain.Bernardo A. MelloAnderson B. BeserraYuhai TuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Bernardo A. Mello Anderson B. Beserra Yuhai Tu Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
description	Bacterial chemoreceptors have multiple methylation sites, but whether the order of methylation matters is unclear. Here, the authors show that sequentially ordered methylation is critical for perfect adaptation and for attenuating the trade-off between accurate adaptation and high response gain.
format	article
author	Bernardo A. Mello Anderson B. Beserra Yuhai Tu
author_facet	Bernardo A. Mello Anderson B. Beserra Yuhai Tu
author_sort	Bernardo A. Mello
title	Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
title_short	Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
title_full	Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
title_fullStr	Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
title_full_unstemmed	Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
title_sort	sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b2276006704844bcbbc28291af6c48e2
work_keys_str_mv	AT bernardoamello sequentialmodificationofbacterialchemoreceptorsiskeyforachievingbothaccurateadaptationandhighgain AT andersonbbeserra sequentialmodificationofbacterialchemoreceptorsiskeyforachievingbothaccurateadaptationandhighgain AT yuhaitu sequentialmodificationofbacterialchemoreceptorsiskeyforachievingbothaccurateadaptationandhighgain
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Sequential modification of bacterial chemoreceptors is key for achieving both accurate adaptation and high gain

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