Perturbing proteomes at single residue resolution using base editing

Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.

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Autores principales: Philippe C. Després, Alexandre K. Dubé, Motoaki Seki, Nozomu Yachie, Christian R. Landry
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b227619047ad4389a7f03d66669a8b2b
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spelling oai:doaj.org-article:b227619047ad4389a7f03d66669a8b2b2021-12-02T17:32:29ZPerturbing proteomes at single residue resolution using base editing10.1038/s41467-020-15796-72041-1723https://doaj.org/article/b227619047ad4389a7f03d66669a8b2b2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15796-7https://doaj.org/toc/2041-1723Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.Philippe C. DesprésAlexandre K. DubéMotoaki SekiNozomu YachieChristian R. LandryNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Philippe C. Després
Alexandre K. Dubé
Motoaki Seki
Nozomu Yachie
Christian R. Landry
Perturbing proteomes at single residue resolution using base editing
description Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.
format article
author Philippe C. Després
Alexandre K. Dubé
Motoaki Seki
Nozomu Yachie
Christian R. Landry
author_facet Philippe C. Després
Alexandre K. Dubé
Motoaki Seki
Nozomu Yachie
Christian R. Landry
author_sort Philippe C. Després
title Perturbing proteomes at single residue resolution using base editing
title_short Perturbing proteomes at single residue resolution using base editing
title_full Perturbing proteomes at single residue resolution using base editing
title_fullStr Perturbing proteomes at single residue resolution using base editing
title_full_unstemmed Perturbing proteomes at single residue resolution using base editing
title_sort perturbing proteomes at single residue resolution using base editing
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b227619047ad4389a7f03d66669a8b2b
work_keys_str_mv AT philippecdespres perturbingproteomesatsingleresidueresolutionusingbaseediting
AT alexandrekdube perturbingproteomesatsingleresidueresolutionusingbaseediting
AT motoakiseki perturbingproteomesatsingleresidueresolutionusingbaseediting
AT nozomuyachie perturbingproteomesatsingleresidueresolutionusingbaseediting
AT christianrlandry perturbingproteomesatsingleresidueresolutionusingbaseediting
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