Perturbing proteomes at single residue resolution using base editing
Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.
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Nature Portfolio
2020
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oai:doaj.org-article:b227619047ad4389a7f03d66669a8b2b2021-12-02T17:32:29ZPerturbing proteomes at single residue resolution using base editing10.1038/s41467-020-15796-72041-1723https://doaj.org/article/b227619047ad4389a7f03d66669a8b2b2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15796-7https://doaj.org/toc/2041-1723Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome.Philippe C. DesprésAlexandre K. DubéMotoaki SekiNozomu YachieChristian R. LandryNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Philippe C. Després Alexandre K. Dubé Motoaki Seki Nozomu Yachie Christian R. Landry Perturbing proteomes at single residue resolution using base editing |
description |
Base editors allow for the precise modification of genes. Here the authors use Target-AID to systematically test 17,000 sites across the yeast genome. |
format |
article |
author |
Philippe C. Després Alexandre K. Dubé Motoaki Seki Nozomu Yachie Christian R. Landry |
author_facet |
Philippe C. Després Alexandre K. Dubé Motoaki Seki Nozomu Yachie Christian R. Landry |
author_sort |
Philippe C. Després |
title |
Perturbing proteomes at single residue resolution using base editing |
title_short |
Perturbing proteomes at single residue resolution using base editing |
title_full |
Perturbing proteomes at single residue resolution using base editing |
title_fullStr |
Perturbing proteomes at single residue resolution using base editing |
title_full_unstemmed |
Perturbing proteomes at single residue resolution using base editing |
title_sort |
perturbing proteomes at single residue resolution using base editing |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b227619047ad4389a7f03d66669a8b2b |
work_keys_str_mv |
AT philippecdespres perturbingproteomesatsingleresidueresolutionusingbaseediting AT alexandrekdube perturbingproteomesatsingleresidueresolutionusingbaseediting AT motoakiseki perturbingproteomesatsingleresidueresolutionusingbaseediting AT nozomuyachie perturbingproteomesatsingleresidueresolutionusingbaseediting AT christianrlandry perturbingproteomesatsingleresidueresolutionusingbaseediting |
_version_ |
1718380270045888512 |