Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients

Background: Hepatocellular carcinoma (HCC) is among the leading causes of cancer deaths in China. Considering its poor prognosis when diagnosed late, Chinese guidelines recommend biannual screening for HCC with abdominal ultrasound and serum α-fetoprotein (AFP) test for high-risk populations. Object...

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Autores principales:	Kerui Xu, Shinobu Watanabe-Galloway, Fedja A. Rochling, Jianjun Zhang, Paraskevi A. Farazi, Hongyan Peng, Hongmei Wang, Jiangtao Luo
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2017
Materias:	hepatocellular carcinoma high-risk Chinese patients screening knowledge barriers Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/b22dde2c44774b25a58ec021e3d3ab02
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spelling	oai:doaj.org-article:b22dde2c44774b25a58ec021e3d3ab022021-12-02T05:17:15ZPractice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients2214-999610.1016/j.aogh.2017.02.002https://doaj.org/article/b22dde2c44774b25a58ec021e3d3ab022017-04-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/193https://doaj.org/toc/2214-9996Background: Hepatocellular carcinoma (HCC) is among the leading causes of cancer deaths in China. Considering its poor prognosis when diagnosed late, Chinese guidelines recommend biannual screening for HCC with abdominal ultrasound and serum α-fetoprotein (AFP) test for high-risk populations. Objectives: To investigate the practice, knowledge, and self-perceived barriers for HCC screening among high-risk hospital patients in China. Methods: An interview-based questionnaire was conducted among Chinese patients with chronic hepatitis B and/or chronic hepatitis C infection from outpatient clinics at 2 tertiary medical institutions in Shanghai and Wuhan, China. Findings: Among 352 participating patients, 50.0% had routine screening, 23.3% had irregular screening, and 26.7% had incomplete or no screening. Significant determinants for screening included higher level of education, underlying liver cirrhosis, a family history of HCC, and better knowledge concerning viral hepatitis, HCC, and HCC screening guidelines. Moreover, factors associated with better knowledge were younger age, female gender, urban residency, education level of college or above, annual household income of greater than 150,000 RMB, and longer duration of hepatitis infection. The 3 most common barriers reported for not receiving screening were not aware that screening for HCC exists (41.5%), no symptoms or discomfort (38.3%), and lack of recommendation from physicians (31.9%). Conlusions: Health care professionals and community leaders should actively inform patients regarding the benefits of HCC screening through design of educational programs. Such interventions are expected to increase knowledge about HCC and HCC screening, as well as improve screening adherence and earlier diagnosis.Kerui XuShinobu Watanabe-GallowayFedja A. RochlingJianjun ZhangParaskevi A. FaraziHongyan PengHongmei WangJiangtao LuoUbiquity Pressarticlehepatocellular carcinomahigh-risk Chinese patientsscreeningknowledgebarriersInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 83, Iss 2, Pp 281-292 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	hepatocellular carcinoma high-risk Chinese patients screening knowledge barriers Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	hepatocellular carcinoma high-risk Chinese patients screening knowledge barriers Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Kerui Xu Shinobu Watanabe-Galloway Fedja A. Rochling Jianjun Zhang Paraskevi A. Farazi Hongyan Peng Hongmei Wang Jiangtao Luo Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
description	Background: Hepatocellular carcinoma (HCC) is among the leading causes of cancer deaths in China. Considering its poor prognosis when diagnosed late, Chinese guidelines recommend biannual screening for HCC with abdominal ultrasound and serum α-fetoprotein (AFP) test for high-risk populations. Objectives: To investigate the practice, knowledge, and self-perceived barriers for HCC screening among high-risk hospital patients in China. Methods: An interview-based questionnaire was conducted among Chinese patients with chronic hepatitis B and/or chronic hepatitis C infection from outpatient clinics at 2 tertiary medical institutions in Shanghai and Wuhan, China. Findings: Among 352 participating patients, 50.0% had routine screening, 23.3% had irregular screening, and 26.7% had incomplete or no screening. Significant determinants for screening included higher level of education, underlying liver cirrhosis, a family history of HCC, and better knowledge concerning viral hepatitis, HCC, and HCC screening guidelines. Moreover, factors associated with better knowledge were younger age, female gender, urban residency, education level of college or above, annual household income of greater than 150,000 RMB, and longer duration of hepatitis infection. The 3 most common barriers reported for not receiving screening were not aware that screening for HCC exists (41.5%), no symptoms or discomfort (38.3%), and lack of recommendation from physicians (31.9%). Conlusions: Health care professionals and community leaders should actively inform patients regarding the benefits of HCC screening through design of educational programs. Such interventions are expected to increase knowledge about HCC and HCC screening, as well as improve screening adherence and earlier diagnosis.
format	article
author	Kerui Xu Shinobu Watanabe-Galloway Fedja A. Rochling Jianjun Zhang Paraskevi A. Farazi Hongyan Peng Hongmei Wang Jiangtao Luo
author_facet	Kerui Xu Shinobu Watanabe-Galloway Fedja A. Rochling Jianjun Zhang Paraskevi A. Farazi Hongyan Peng Hongmei Wang Jiangtao Luo
author_sort	Kerui Xu
title	Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
title_short	Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
title_full	Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
title_fullStr	Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
title_full_unstemmed	Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients
title_sort	practice, knowledge, and barriers for screening of hepatocellular carcinoma among high-risk chinese patients
publisher	Ubiquity Press
publishDate	2017
url	https://doaj.org/article/b22dde2c44774b25a58ec021e3d3ab02
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Practice, Knowledge, and Barriers for Screening of Hepatocellular Carcinoma Among High-Risk Chinese Patients

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