Computational modeling of interactions between multiple myeloma and the bone microenvironment.

Multiple Myeloma (MM) is a B-cell malignancy that is characterized by osteolytic bone lesions. It has been postulated that positive feedback loops in the interactions between MM cells and the bone microenvironment form reinforcing 'vicious cycles', resulting in more bone resorption and MM...

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Autores principales: Yan Wang, Peter Pivonka, Pascal R Buenzli, David W Smith, Colin R Dunstan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/b22ee497c3de41179f4f5ba667341407
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