HSPA9/Mortalin mediates axo-protection and modulates mitochondrial dynamics in neurons

Abstract Mortalin is a mitochondrial chaperone protein involved in quality control of proteins imported into the mitochondrial matrix, which was recently described as a sensor of neuronal stress. Mortalin is down-regulated in neurons of patients with neurodegenerative diseases and levels of Mortalin...

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Autores principales: Cécile A. Ferré, Anne Thouard, Alexandre Bétourné, Anne-Louise Le Dorze, Pascale Belenguer, Marie-Christine Miquel, Jean-Michel Peyrin, Daniel Gonzalez-Dunia, Marion Szelechowski
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b237ff1101164e3aab9e0784ffce70d4
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