Positive affect, surprise, and fatigue are correlates of network flexibility

Abstract Advances in neuroimaging have made it possible to reconstruct functional networks from the activity patterns of brain regions distributed across the cerebral cortex. Recent work has shown that flexible reconfiguration of human brain networks over short timescales supports cognitive flexibil...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Richard F. Betzel, Theodore D. Satterthwaite, Joshua I. Gold, Danielle S. Bassett
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b2394ef4b3b54b6c970a8c3d1fc8d423
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b2394ef4b3b54b6c970a8c3d1fc8d423
record_format	dspace
spelling	oai:doaj.org-article:b2394ef4b3b54b6c970a8c3d1fc8d4232021-12-02T12:31:59ZPositive affect, surprise, and fatigue are correlates of network flexibility10.1038/s41598-017-00425-z2045-2322https://doaj.org/article/b2394ef4b3b54b6c970a8c3d1fc8d4232017-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00425-zhttps://doaj.org/toc/2045-2322Abstract Advances in neuroimaging have made it possible to reconstruct functional networks from the activity patterns of brain regions distributed across the cerebral cortex. Recent work has shown that flexible reconfiguration of human brain networks over short timescales supports cognitive flexibility and learning. However, modulating network flexibility to enhance learning requires an understanding of an as-yet unknown relationship between flexibility and brain state. Here, we investigate the relationship between network flexibility and affect, leveraging an unprecedented longitudinal data set. We demonstrate that indices associated with positive mood and surprise are both associated with network flexibility – positive mood portends a more flexible brain while increased levels of surprise portend a less flexible brain. In both cases, these relationships are driven predominantly by a subset of brain regions comprising the somatomotor system. Our results simultaneously suggest a network-level mechanism underlying learning deficits in mood disorders as well as a potential target – altering an individual’s mood or task novelty – to improve learning.Richard F. BetzelTheodore D. SatterthwaiteJoshua I. GoldDanielle S. BassettNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Richard F. Betzel Theodore D. Satterthwaite Joshua I. Gold Danielle S. Bassett Positive affect, surprise, and fatigue are correlates of network flexibility
description	Abstract Advances in neuroimaging have made it possible to reconstruct functional networks from the activity patterns of brain regions distributed across the cerebral cortex. Recent work has shown that flexible reconfiguration of human brain networks over short timescales supports cognitive flexibility and learning. However, modulating network flexibility to enhance learning requires an understanding of an as-yet unknown relationship between flexibility and brain state. Here, we investigate the relationship between network flexibility and affect, leveraging an unprecedented longitudinal data set. We demonstrate that indices associated with positive mood and surprise are both associated with network flexibility – positive mood portends a more flexible brain while increased levels of surprise portend a less flexible brain. In both cases, these relationships are driven predominantly by a subset of brain regions comprising the somatomotor system. Our results simultaneously suggest a network-level mechanism underlying learning deficits in mood disorders as well as a potential target – altering an individual’s mood or task novelty – to improve learning.
format	article
author	Richard F. Betzel Theodore D. Satterthwaite Joshua I. Gold Danielle S. Bassett
author_facet	Richard F. Betzel Theodore D. Satterthwaite Joshua I. Gold Danielle S. Bassett
author_sort	Richard F. Betzel
title	Positive affect, surprise, and fatigue are correlates of network flexibility
title_short	Positive affect, surprise, and fatigue are correlates of network flexibility
title_full	Positive affect, surprise, and fatigue are correlates of network flexibility
title_fullStr	Positive affect, surprise, and fatigue are correlates of network flexibility
title_full_unstemmed	Positive affect, surprise, and fatigue are correlates of network flexibility
title_sort	positive affect, surprise, and fatigue are correlates of network flexibility
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b2394ef4b3b54b6c970a8c3d1fc8d423
work_keys_str_mv	AT richardfbetzel positiveaffectsurpriseandfatiguearecorrelatesofnetworkflexibility AT theodoredsatterthwaite positiveaffectsurpriseandfatiguearecorrelatesofnetworkflexibility AT joshuaigold positiveaffectsurpriseandfatiguearecorrelatesofnetworkflexibility AT daniellesbassett positiveaffectsurpriseandfatiguearecorrelatesofnetworkflexibility
_version_	1718394236124004352

Positive affect, surprise, and fatigue are correlates of network flexibility

Ejemplares similares