Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors.
Activation of T cells through the engagement of the T cell receptors (TCRs) with specific peptide-MHC complexes on antigen presenting cells (APCs) is the major determinant for their proliferation, differentiation and display of effector functions. To assess the role of quantity and quality of peptid...
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Auteurs principaux: | Qi Wan, Lina Kozhaya, Keren Imberg, Frances Mercer, Shi Zhong, Michelle Krogsgaard, Derya Unutmaz |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2013
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Accès en ligne: | https://doaj.org/article/b23f7f5023444eb2a4eb7065231ba18b |
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