Probing the effector and suppressive functions of human T cell subsets using antigen-specific engineered T cell receptors.
Activation of T cells through the engagement of the T cell receptors (TCRs) with specific peptide-MHC complexes on antigen presenting cells (APCs) is the major determinant for their proliferation, differentiation and display of effector functions. To assess the role of quantity and quality of peptid...
Guardado en:
Autores principales: | Qi Wan, Lina Kozhaya, Keren Imberg, Frances Mercer, Shi Zhong, Michelle Krogsgaard, Derya Unutmaz |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/b23f7f5023444eb2a4eb7065231ba18b |
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