Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neonatal anthropomorphic indicators of placental insuff...

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Autores principales: Tu’uhevaha J. Kaitu’u-Lino, Teresa M. MacDonald, Ping Cannon, Tuong-Vi Nguyen, Richard J. Hiscock, Nick Haan, Jenny E. Myers, Roxanne Hastie, Kirsten M. Dane, Anna L. Middleton, Intissar Bittar, Amanda N. Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J. Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P. Walker, Stephen Tong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/b241206eb8c94b78bb67bfb73fc52e4f
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Sumario:There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neonatal anthropomorphic indicators of placental insufficiency.

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