Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neonatal anthropomorphic indicators of placental insuff...

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Autores principales:	Tu’uhevaha J. Kaitu’u-Lino, Teresa M. MacDonald, Ping Cannon, Tuong-Vi Nguyen, Richard J. Hiscock, Nick Haan, Jenny E. Myers, Roxanne Hastie, Kirsten M. Dane, Anna L. Middleton, Intissar Bittar, Amanda N. Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J. Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P. Walker, Stephen Tong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b241206eb8c94b78bb67bfb73fc52e4f
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spelling	oai:doaj.org-article:b241206eb8c94b78bb67bfb73fc52e4f2021-12-02T15:54:44ZCirculating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction10.1038/s41467-020-16346-x2041-1723https://doaj.org/article/b241206eb8c94b78bb67bfb73fc52e4f2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16346-xhttps://doaj.org/toc/2041-1723There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neonatal anthropomorphic indicators of placental insufficiency.Tu’uhevaha J. Kaitu’u-LinoTeresa M. MacDonaldPing CannonTuong-Vi NguyenRichard J. HiscockNick HaanJenny E. MyersRoxanne HastieKirsten M. DaneAnna L. MiddletonIntissar BittarAmanda N. Sferruzzi-PerriNatasha PritchardAlesia HarperNatalie J. HannanValerie KyritsisNick CrinisLisa HuiSusan P. WalkerStephen TongNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tu’uhevaha J. Kaitu’u-Lino Teresa M. MacDonald Ping Cannon Tuong-Vi Nguyen Richard J. Hiscock Nick Haan Jenny E. Myers Roxanne Hastie Kirsten M. Dane Anna L. Middleton Intissar Bittar Amanda N. Sferruzzi-Perri Natasha Pritchard Alesia Harper Natalie J. Hannan Valerie Kyritsis Nick Crinis Lisa Hui Susan P. Walker Stephen Tong Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
description	There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neonatal anthropomorphic indicators of placental insufficiency.
format	article
author	Tu’uhevaha J. Kaitu’u-Lino Teresa M. MacDonald Ping Cannon Tuong-Vi Nguyen Richard J. Hiscock Nick Haan Jenny E. Myers Roxanne Hastie Kirsten M. Dane Anna L. Middleton Intissar Bittar Amanda N. Sferruzzi-Perri Natasha Pritchard Alesia Harper Natalie J. Hannan Valerie Kyritsis Nick Crinis Lisa Hui Susan P. Walker Stephen Tong
author_facet	Tu’uhevaha J. Kaitu’u-Lino Teresa M. MacDonald Ping Cannon Tuong-Vi Nguyen Richard J. Hiscock Nick Haan Jenny E. Myers Roxanne Hastie Kirsten M. Dane Anna L. Middleton Intissar Bittar Amanda N. Sferruzzi-Perri Natasha Pritchard Alesia Harper Natalie J. Hannan Valerie Kyritsis Nick Crinis Lisa Hui Susan P. Walker Stephen Tong
author_sort	Tu’uhevaha J. Kaitu’u-Lino
title	Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
title_short	Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
title_full	Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
title_fullStr	Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
title_full_unstemmed	Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
title_sort	circulating spint1 is a biomarker of pregnancies with poor placental function and fetal growth restriction
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b241206eb8c94b78bb67bfb73fc52e4f
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Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

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