Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability

Keith Raymond Pine,1 Brian Sloan,2 KyuYeon Ivy Han,1 Simon Swift,3 Robert John Jacobs11Department of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand; 2New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand;...

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Autores principales:	Pine KR, Sloan B, Han KYI, Swift S, Jacobs RJ
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b245c2df71c1477985ddb49ec63fa49d
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spelling	oai:doaj.org-article:b245c2df71c1477985ddb49ec63fa49d2021-12-02T06:10:30ZDeposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability1177-54671177-5483https://doaj.org/article/b245c2df71c1477985ddb49ec63fa49d2013-02-01T00:00:00Zhttp://www.dovepress.com/deposit-buildup-on-prosthetic-eye-material-in-vitro-and-its-effect-on--a12206https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Keith Raymond Pine,1 Brian Sloan,2 KyuYeon Ivy Han,1 Simon Swift,3 Robert John Jacobs11Department of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand; 2New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand; 3Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New ZealandBackground: The aim of this in-vitro study was to investigate the effect of different polishing standards on prosthetic eye material (poly(methyl methacrylate) [PMMA]) on surface wettability and the rate of protein and lipid buildup.Methods: Sample disks (12 mm diameter &times; 1 mm thickness) of PMMA were polished to three different standards of surface finish: low, normal, and optical quality contact lens standard. The sample disks were incubated in a protein-rich artificial tear solution (ATS) for the following periods of time: 1 second, 30 minutes, 1 hour, 4 hours, 24 hours, and 14 days. Surface wettability was measured with a goniometer before and after protein deposits were removed. One-way analysis of variance and paired-samples t-test were used for the statistical analysis.Results: Between 13.64 and 62.88 &micro;g of protein adhered to the sample disks immediately upon immersion in ATS. Sample disks with the highest polish attracted less protein deposits. The sample disks polished to optical quality contact lens standard were more wettable than those less highly polished, and wettability significantly decreased following removal of protein deposits. The addition of lipids to protein-only ATS made no difference to the amount of protein deposited on the sample disks for any of the standards of surface polish tested.Conclusion: The findings are consistent with the results of the in-vivo investigation reported previously by the authors. Our view that the minimum standard of polish for prosthetic eyes should be optical quality contact lens standard and that deposits on PMMA prosthetic eyes improve the lubricating properties of the socket fluids has been reinforced by the results of this study.Keywords: protein deposits, surface polish, PMMAPine KRSloan BHan KYISwift SJacobs RJDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 313-319 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Pine KR Sloan B Han KYI Swift S Jacobs RJ Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
description	Keith Raymond Pine,1 Brian Sloan,2 KyuYeon Ivy Han,1 Simon Swift,3 Robert John Jacobs11Department of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand; 2New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand; 3Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New ZealandBackground: The aim of this in-vitro study was to investigate the effect of different polishing standards on prosthetic eye material (poly(methyl methacrylate) [PMMA]) on surface wettability and the rate of protein and lipid buildup.Methods: Sample disks (12 mm diameter &times; 1 mm thickness) of PMMA were polished to three different standards of surface finish: low, normal, and optical quality contact lens standard. The sample disks were incubated in a protein-rich artificial tear solution (ATS) for the following periods of time: 1 second, 30 minutes, 1 hour, 4 hours, 24 hours, and 14 days. Surface wettability was measured with a goniometer before and after protein deposits were removed. One-way analysis of variance and paired-samples t-test were used for the statistical analysis.Results: Between 13.64 and 62.88 &micro;g of protein adhered to the sample disks immediately upon immersion in ATS. Sample disks with the highest polish attracted less protein deposits. The sample disks polished to optical quality contact lens standard were more wettable than those less highly polished, and wettability significantly decreased following removal of protein deposits. The addition of lipids to protein-only ATS made no difference to the amount of protein deposited on the sample disks for any of the standards of surface polish tested.Conclusion: The findings are consistent with the results of the in-vivo investigation reported previously by the authors. Our view that the minimum standard of polish for prosthetic eyes should be optical quality contact lens standard and that deposits on PMMA prosthetic eyes improve the lubricating properties of the socket fluids has been reinforced by the results of this study.Keywords: protein deposits, surface polish, PMMA
format	article
author	Pine KR Sloan B Han KYI Swift S Jacobs RJ
author_facet	Pine KR Sloan B Han KYI Swift S Jacobs RJ
author_sort	Pine KR
title	Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
title_short	Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
title_full	Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
title_fullStr	Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
title_full_unstemmed	Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
title_sort	deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/b245c2df71c1477985ddb49ec63fa49d
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Deposit buildup on prosthetic eye material (in vitro) and its effect on surface wettability

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