Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins).

Glycosidases are associated with various human diseases. The development of efficient and specific inhibitors may provide powerful tools to modulate their activity. However, achieving high selectivity is a major challenge given that glycosidases with different functions can have similar enzymatic me...

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Bibliographic Details
Main Authors: Agustín Correa, Sabino Pacheco, Ariel E Mechaly, Gonzalo Obal, Ghislaine Béhar, Barbara Mouratou, Pablo Oppezzo, Pedro M Alzari, Frédéric Pecorari
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/b257c58438d04cc4a4c882f220efb2f0
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