ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling.

ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling.

High expression of the E26 transforming sequence related gene (ERG) is associated with poor prognosis in a subgroup of leukemia patients with acute myeloid (AML) and acute T-lymphoblastic leukemia (T-ALL). In a previous study we proposed that ERG overexpression may deregulate several signaling casca...

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Autores principales: Juliane Bock, Liliana H Mochmann, Cornelia Schlee, Nasrin Farhadi-Sartangi, Stefanie Göllner, Carsten Müller-Tidow, Claudia D Baldus
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/b25b4eced5084ebe887e88f653624dea
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