Imaging and kinetics of the bimolecular complex formed by the tumor suppressor p53 with ubiquitin ligase COP1 as studied by atomic force microscopy and surface plasmon resonance

Ilaria Moscetti, Anna Rita Bizzarri, Salvatore Cannistraro Biophysics and Nanoscience Centre, Department of Ecology and Biology, Università della Tuscia, Viterbo, Italy Abstract: p53 plays an important role in the safeguard of the genome but it is frequently downregulated mainly by E3 u...

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Bibliographic Details
Main Authors: Moscetti I, Bizzarri AR, Cannistraro S
Format: article
Language:EN
Published: Dove Medical Press 2018
Subjects:
p53
AFM
AFS
SPR
Online Access:https://doaj.org/article/b25b83b5d0714378a52a9e11da1ba33e
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