DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts
Accumulating evidence suggests that developmentally regulated GTP-binding protein 2 (DRG2), an evolutionarily conserved GTP-binding protein, plays an important role in regulating cell growth, inflammation, and mitochondria dynamics. However, the effect of DRG2 in aging remains unclear. In this study...
Guardado en:
Autores principales: | Bing Si Li, Ai Lin Jin, ZiQi Zhou, Jae Ho Seo, Byung-Min Choi |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Hindawi Limited
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b264a996a4ca4be2b007eae02a2c2d4d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Circ-SIRT1 inhibits cardiac hypertrophy via activating SIRT1 to promote autophagy
por: Weichen Wang, et al.
Publicado: (2021) -
Tubeimoside I Ameliorates Myocardial Ischemia-Reperfusion Injury through SIRT3-Dependent Regulation of Oxidative Stress and Apoptosis
por: Dingyi Lv, et al.
Publicado: (2021) -
Echinacoside Upregulates Sirt1 to Suppress Endoplasmic Reticulum Stress and Inhibit Extracellular Matrix Degradation In Vitro and Ameliorates Osteoarthritis In Vivo
por: Zhen Lin, et al.
Publicado: (2021) -
Lactobacillus rhamnosus GG Colonization in Early Life Ameliorates Inflammaging of Offspring by Activating SIRT1/AMPK/PGC-1α Pathway
por: Tianyu Liu, et al.
Publicado: (2021) -
Functional delivery of lncRNA TUG1 by endothelial progenitor cells derived extracellular vesicles confers anti-inflammatory macrophage polarization in sepsis via impairing miR-9-5p-targeted SIRT1 inhibition
por: Wentao Ma, et al.
Publicado: (2021)