DRG2 Accelerates Senescence via Negative Regulation of SIRT1 in Human Diploid Fibroblasts

Accumulating evidence suggests that developmentally regulated GTP-binding protein 2 (DRG2), an evolutionarily conserved GTP-binding protein, plays an important role in regulating cell growth, inflammation, and mitochondria dynamics. However, the effect of DRG2 in aging remains unclear. In this study...

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Bibliographic Details
Main Authors: Bing Si Li, Ai Lin Jin, ZiQi Zhou, Jae Ho Seo, Byung-Min Choi
Format: article
Language:EN
Published: Hindawi Limited 2021
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Online Access:https://doaj.org/article/b264a996a4ca4be2b007eae02a2c2d4d
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