Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.

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Autores principales:	Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b27038dc2f1b4d289d890a458f664987
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spelling	oai:doaj.org-article:b27038dc2f1b4d289d890a458f6649872021-12-02T16:14:58ZSynucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling10.1038/s41467-020-17328-92041-1723https://doaj.org/article/b27038dc2f1b4d289d890a458f6649872020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17328-9https://doaj.org/toc/2041-1723The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.Federico N. SoriaChiara PavioloEvelyne DoudnikoffMarie-Laure ArotcarenaAntony LeeNoémie DannéAmit Kumar MandalPhilippe GossetBenjamin DehayLaurent GrocLaurent CognetErwan BezardNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Federico N. Soria Chiara Paviolo Evelyne Doudnikoff Marie-Laure Arotcarena Antony Lee Noémie Danné Amit Kumar Mandal Philippe Gosset Benjamin Dehay Laurent Groc Laurent Cognet Erwan Bezard Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
description	The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.
format	article
author	Federico N. Soria Chiara Paviolo Evelyne Doudnikoff Marie-Laure Arotcarena Antony Lee Noémie Danné Amit Kumar Mandal Philippe Gosset Benjamin Dehay Laurent Groc Laurent Cognet Erwan Bezard
author_facet	Federico N. Soria Chiara Paviolo Evelyne Doudnikoff Marie-Laure Arotcarena Antony Lee Noémie Danné Amit Kumar Mandal Philippe Gosset Benjamin Dehay Laurent Groc Laurent Cognet Erwan Bezard
author_sort	Federico N. Soria
title	Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
title_short	Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
title_full	Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
title_fullStr	Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
title_full_unstemmed	Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
title_sort	synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/b27038dc2f1b4d289d890a458f664987
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Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling

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