Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
The nanoscale organisation of the brain extracellular space can be studied in vivo. Here, the authors investigate how it changes in response to α-synuclein pathology, and identify interactions between microglia and the extracellular matrix.
Guardado en:
Autores principales: | Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b27038dc2f1b4d289d890a458f664987 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques
por: Marie-Laure Arotcarena, et al.
Publicado: (2021) -
Autophagy in α-Synucleinopathies—An Overstrained System
por: Lisa Fellner, et al.
Publicado: (2021) -
Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
por: Juan A. Varela, et al.
Publicado: (2016) -
Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy
por: Souvarish Sarkar, et al.
Publicado: (2020) -
Il-10 signaling reduces survival in mouse models of synucleinopathy
por: Samuel G. Cockey, et al.
Publicado: (2021)