A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Alternative RNA splicing varies across the brain. Its mapping at single cell resolution is unclear. Here, the authors provide a spatial and single-cell splicing atlas reporting brain region- and cell type-specific expression of different isoforms in the postnatal mouse brain.

Guardado en:
Detalles Bibliográficos
Autores principales: Anoushka Joglekar, Andrey Prjibelski, Ahmed Mahfouz, Paul Collier, Susan Lin, Anna Katharina Schlusche, Jordan Marrocco, Stephen R. Williams, Bettina Haase, Ashley Hayes, Jennifer G. Chew, Neil I. Weisenfeld, Man Ying Wong, Alexander N. Stein, Simon A. Hardwick, Toby Hunt, Qi Wang, Christoph Dieterich, Zachary Bent, Olivier Fedrigo, Steven A. Sloan, Davide Risso, Erich D. Jarvis, Paul Flicek, Wenjie Luo, Geoffrey S. Pitt, Adam Frankish, August B. Smit, M. Elizabeth Ross, Hagen U. Tilgner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/b27a2afb47544e009093959c837b41e3
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:b27a2afb47544e009093959c837b41e3
record_format dspace
spelling oai:doaj.org-article:b27a2afb47544e009093959c837b41e32021-12-02T13:57:03ZA spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain10.1038/s41467-020-20343-52041-1723https://doaj.org/article/b27a2afb47544e009093959c837b41e32021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20343-5https://doaj.org/toc/2041-1723Alternative RNA splicing varies across the brain. Its mapping at single cell resolution is unclear. Here, the authors provide a spatial and single-cell splicing atlas reporting brain region- and cell type-specific expression of different isoforms in the postnatal mouse brain.Anoushka JoglekarAndrey PrjibelskiAhmed MahfouzPaul CollierSusan LinAnna Katharina SchluscheJordan MarroccoStephen R. WilliamsBettina HaaseAshley HayesJennifer G. ChewNeil I. WeisenfeldMan Ying WongAlexander N. SteinSimon A. HardwickToby HuntQi WangChristoph DieterichZachary BentOlivier FedrigoSteven A. SloanDavide RissoErich D. JarvisPaul FlicekWenjie LuoGeoffrey S. PittAdam FrankishAugust B. SmitM. Elizabeth RossHagen U. TilgnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Anoushka Joglekar
Andrey Prjibelski
Ahmed Mahfouz
Paul Collier
Susan Lin
Anna Katharina Schlusche
Jordan Marrocco
Stephen R. Williams
Bettina Haase
Ashley Hayes
Jennifer G. Chew
Neil I. Weisenfeld
Man Ying Wong
Alexander N. Stein
Simon A. Hardwick
Toby Hunt
Qi Wang
Christoph Dieterich
Zachary Bent
Olivier Fedrigo
Steven A. Sloan
Davide Risso
Erich D. Jarvis
Paul Flicek
Wenjie Luo
Geoffrey S. Pitt
Adam Frankish
August B. Smit
M. Elizabeth Ross
Hagen U. Tilgner
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
description Alternative RNA splicing varies across the brain. Its mapping at single cell resolution is unclear. Here, the authors provide a spatial and single-cell splicing atlas reporting brain region- and cell type-specific expression of different isoforms in the postnatal mouse brain.
format article
author Anoushka Joglekar
Andrey Prjibelski
Ahmed Mahfouz
Paul Collier
Susan Lin
Anna Katharina Schlusche
Jordan Marrocco
Stephen R. Williams
Bettina Haase
Ashley Hayes
Jennifer G. Chew
Neil I. Weisenfeld
Man Ying Wong
Alexander N. Stein
Simon A. Hardwick
Toby Hunt
Qi Wang
Christoph Dieterich
Zachary Bent
Olivier Fedrigo
Steven A. Sloan
Davide Risso
Erich D. Jarvis
Paul Flicek
Wenjie Luo
Geoffrey S. Pitt
Adam Frankish
August B. Smit
M. Elizabeth Ross
Hagen U. Tilgner
author_facet Anoushka Joglekar
Andrey Prjibelski
Ahmed Mahfouz
Paul Collier
Susan Lin
Anna Katharina Schlusche
Jordan Marrocco
Stephen R. Williams
Bettina Haase
Ashley Hayes
Jennifer G. Chew
Neil I. Weisenfeld
Man Ying Wong
Alexander N. Stein
Simon A. Hardwick
Toby Hunt
Qi Wang
Christoph Dieterich
Zachary Bent
Olivier Fedrigo
Steven A. Sloan
Davide Risso
Erich D. Jarvis
Paul Flicek
Wenjie Luo
Geoffrey S. Pitt
Adam Frankish
August B. Smit
M. Elizabeth Ross
Hagen U. Tilgner
author_sort Anoushka Joglekar
title A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
title_short A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
title_full A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
title_fullStr A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
title_full_unstemmed A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
title_sort spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b27a2afb47544e009093959c837b41e3
work_keys_str_mv AT anoushkajoglekar aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT andreyprjibelski aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT ahmedmahfouz aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT paulcollier aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT susanlin aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT annakatharinaschlusche aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT jordanmarrocco aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT stephenrwilliams aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT bettinahaase aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT ashleyhayes aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT jennifergchew aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT neiliweisenfeld aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT manyingwong aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT alexandernstein aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT simonahardwick aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT tobyhunt aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT qiwang aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT christophdieterich aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT zacharybent aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT olivierfedrigo aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT stevenasloan aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT daviderisso aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT erichdjarvis aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT paulflicek aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT wenjieluo aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT geoffreyspitt aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT adamfrankish aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT augustbsmit aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT melizabethross aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT hagenutilgner aspatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT anoushkajoglekar spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT andreyprjibelski spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT ahmedmahfouz spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT paulcollier spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT susanlin spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT annakatharinaschlusche spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT jordanmarrocco spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT stephenrwilliams spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT bettinahaase spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT ashleyhayes spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT jennifergchew spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT neiliweisenfeld spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT manyingwong spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT alexandernstein spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT simonahardwick spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT tobyhunt spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT qiwang spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT christophdieterich spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT zacharybent spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT olivierfedrigo spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT stevenasloan spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT daviderisso spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT erichdjarvis spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT paulflicek spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT wenjieluo spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT geoffreyspitt spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT adamfrankish spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT augustbsmit spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT melizabethross spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
AT hagenutilgner spatiallyresolvedbrainregionandcelltypespecificisoformatlasofthepostnatalmousebrain
_version_ 1718392341611413504

Ejemplares similares