Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions
Rising rates of peanut allergy pose a public health problem. Here, the authors profile blood transcriptomes during double-blind, placebo-controlled oral challenge in peanut-allergic children to identify gene and cell composition changes, and construct causal networks to detect key allergic reaction ...
Guardado en:
Autores principales: | C. T. Watson, A. T. Cohain, R. S. Griffin, Y. Chun, A. Grishin, H. Hacyznska, G. E. Hoffman, N. D. Beckmann, H. Shah, P. Dawson, A. Henning, R. Wood, A. W. Burks, S. M. Jones, D. Y. M. Leung, S. Sicherer, H. A. Sampson, A. J. Sharp, E. E. Schadt, S. Bunyavanich |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b27d5451d40c4093a9beecfb4a22c936 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Elevated antigen-driven IL-9 responses are prominent in peanut allergic humans.
por: Jungang Xie, et al.
Publicado: (2012) -
IgE-associated IGHV genes from venom and peanut allergic individuals lack mutational evidence of antigen selection.
por: Yan Wang, et al.
Publicado: (2014) -
Peanut Sensitivity and Allergic Rhinitis in Young Children are Associated with Attention-Deficit Hyperactivity Disorder Symptoms in Adolescence
por: Guo MMH, et al.
Publicado: (2020) -
Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children.
por: Meiqin Wang, et al.
Publicado: (2020) -
Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice.
por: Lucie Mondoulet, et al.
Publicado: (2012)