Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling
Long noncoding RNAs have been shown to play a role in cardiovascular disease. Here, the authors identify a lncRNA named CCRR, whose downregulation in failing hearts causes cardiac conduction disturbances by altering the endocytic trafficking of Cx43.
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Nature Portfolio
2018
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oai:doaj.org-article:b2856093b13b442281c99532c0c069802021-12-02T17:31:29ZLong non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling10.1038/s41467-018-06637-92041-1723https://doaj.org/article/b2856093b13b442281c99532c0c069802018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06637-9https://doaj.org/toc/2041-1723Long noncoding RNAs have been shown to play a role in cardiovascular disease. Here, the authors identify a lncRNA named CCRR, whose downregulation in failing hearts causes cardiac conduction disturbances by altering the endocytic trafficking of Cx43.Yong ZhangLihua SunLina XuanZhenwei PanXueling HuHongyu LiuYunlong BaiLei JiaoZhange LiLina CuiXiaoxue WangSiqi WangTingting YuBingbing FengYing GuoZonghong LiuWeixin MengHequn RenJiyuan ZhuXuyun ZhaoChao YangYing ZhangChaoqian XuZhiguo WangYanjie LuHongli ShanBaofeng YangNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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DOAJ |
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EN |
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Science Q |
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Science Q Yong Zhang Lihua Sun Lina Xuan Zhenwei Pan Xueling Hu Hongyu Liu Yunlong Bai Lei Jiao Zhange Li Lina Cui Xiaoxue Wang Siqi Wang Tingting Yu Bingbing Feng Ying Guo Zonghong Liu Weixin Meng Hequn Ren Jiyuan Zhu Xuyun Zhao Chao Yang Ying Zhang Chaoqian Xu Zhiguo Wang Yanjie Lu Hongli Shan Baofeng Yang Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
description |
Long noncoding RNAs have been shown to play a role in cardiovascular disease. Here, the authors identify a lncRNA named CCRR, whose downregulation in failing hearts causes cardiac conduction disturbances by altering the endocytic trafficking of Cx43. |
format |
article |
author |
Yong Zhang Lihua Sun Lina Xuan Zhenwei Pan Xueling Hu Hongyu Liu Yunlong Bai Lei Jiao Zhange Li Lina Cui Xiaoxue Wang Siqi Wang Tingting Yu Bingbing Feng Ying Guo Zonghong Liu Weixin Meng Hequn Ren Jiyuan Zhu Xuyun Zhao Chao Yang Ying Zhang Chaoqian Xu Zhiguo Wang Yanjie Lu Hongli Shan Baofeng Yang |
author_facet |
Yong Zhang Lihua Sun Lina Xuan Zhenwei Pan Xueling Hu Hongyu Liu Yunlong Bai Lei Jiao Zhange Li Lina Cui Xiaoxue Wang Siqi Wang Tingting Yu Bingbing Feng Ying Guo Zonghong Liu Weixin Meng Hequn Ren Jiyuan Zhu Xuyun Zhao Chao Yang Ying Zhang Chaoqian Xu Zhiguo Wang Yanjie Lu Hongli Shan Baofeng Yang |
author_sort |
Yong Zhang |
title |
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
title_short |
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
title_full |
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
title_fullStr |
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
title_full_unstemmed |
Long non-coding RNA CCRR controls cardiac conduction via regulating intercellular coupling |
title_sort |
long non-coding rna ccrr controls cardiac conduction via regulating intercellular coupling |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/b2856093b13b442281c99532c0c06980 |
work_keys_str_mv |
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1718380632885690368 |